Caution- Do Not Combine Chemotherapy for Prostate Cancer with Avestin

An article appearing today the Urology Times E-News rang a warning bell about the use of the angiogenesis inhibitor bevacizumab (Avastin). The article warned that men with advanced prostate cancer may be at an increased risk of treatment-related death when bevacizumab is used in combination with other therapies. Senior author Shenhong Wu, MD, PhD, and [...]

The effect of PSA doubling time (PSADT) and Gleason score on the PSA at the time of initial metastasis in men with biochemical recurrence after prostatectomy.

The researchers took a cohort of 430 men with a biochemical recurrence (PSA increase only) after failed prostatectomy. The men underwent observation until they experienced metastatic disease as determined by CT or bone scan. The researchers then evaluated the PSA at the time the men developed metastasis for those patients who developed metastatic disease. PSA [...]

Pomegranate Effects PSADT in Men with Advanced Prostate Cancer

Prostate cancer diets and the use of supplements have continued to be an issue faced by men fighting advanced prostate cancer. Different products seem to fall in and out of vogue; unfortunately we usually have little actual hard data on the real value of any of these products. The use of pomegranate with the goal [...]

One Large Step for Prostate Cancer and One Very Small Step for Men – Whole Genome Sequencing for Prostate Cancer

Yesterday the Prostate Cancer Foundation (PCRF) made a major announcement, it has sequenced the of whole cancer genomes of seven different men with aggressive prostate cancer. This is a historic development in the fight against prostate cancer, however, it is a small step for those of us on the ground. The eventual goal of projects [...]

Timely Use of Zoledronic Acid Provides Both Longer Hospital Free Survival and Increased Survival

A recent study conducted at the Southeast Louisiana Veterans Health Care System, New Orleans, LA, USA by the Section of Hematology and Medical Oncology, Tulane University School of Medicine, New Orleans, LA, evaluated the efficacy of the timely use of zoledronic acid (ZA) on clinical outcomes and health care utilization in men with bone-metastatic prostate [...]

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