Eat that Fish

Most studies on prostate cancer prevention focus on the initial prevention of the cancer. Rarely do we see studies on preventing advanced prostate cancer. Now a study has shown that consuming omega-3 fatty acids appear to protect against developing advanced prostate cancer. In other words, eating a serving of fish each week could dramatically reduce [...]

Can Bone Pain Predict Survival in Men with Metastatic Hormone-Refractory Prostate Cancer Treated with Docetaxel? What are the Implications?

A small study of 145 men with asymptomatic metastatic hormone-refractory prostate cancer (HRPC) was conducted to determine the benefit of starting early chemotherapy with docetaxel. Collected data were analyzed from these subjects who were treated with chemotherapy between February 2000 and June 2002 in one French center. The men were categorized into three groups according [...]

Support Prostate Cancer Research Funding NOW

The Department of Defense manages a significant fund given by congress to finance high risk and high impact research. One of the specific diseases that is funded is prostate cancer. In my personal opinion this particular program has had a significant effect on our lives. Unfortunately, prostate cancer has continued to take a back seat [...]

A Request for Study Subjects

A graduate student, Patrica Ames, has requested that I announce her request for subjects to participate in a study she is performing about clinical trial participants. Here it is: Invitation: Hello. I am reposting this request for volunteers to help me with my PhD research. I am very grateful that some have already spent the [...]

Positive Results from a Phase I-II Trial of MDV3100, Perhaps a New Alternative Hormone Blockade Option

There has been some positive news coming out of the ASCO conference in Florida this past week. One of the most significant pieces of positive news deals with the results of a phase I-II trial of the drug known as MDV3100. Basically, more than half of subjects in the study with castration-resistant prostate cancer responded [...]

Yale Researchers Present Results of Phase II Phenoxodiol Clinical Trial in Prostate Cancer Patients at ASCO 2009 Genitourinary Cancers Symposium

Marshall Edwards, Inc. (NASDAQ: MSHL) is planning to release preliminary results from a Phase II clinical trial of oral phenoxodiol in patients with early and advanced stage prostate cancer. The results will be presented by the Yale researchers, who were responsible for the study, at the ASCO Genitourinary Cancers Symposium in Orlando, Florida; February 26-28, [...]

A Possible Surrogate Endpoint- Circulating Tumor Cells

There is nothing more frustration that the current methods used by the FDA to approve drugs. The theory is great, but how it gets translated into our real world is killer, I mean a literal killer of men. The FDA wants assurances that before they approve a drug that it really works, or shows efficacy. [...]

Algeta, Completing A Successful Phase II Trial For Men With Bone Metastases Will Begin Enrolling US Survivors Into A Phase III Trial

Algeta ASA (OSE: ALGETA), has announced that it will begin to enroll US survivors into its Alsympca phase III trial evaluating Alpharadin (radium-223). Alpharadin is designed to be used as a treatment for bone metastases in prostate cancer survivors with hormone-refractory prostate cancer (HRPC). The announcement of the trial follows a successful end-of-phase II meeting [...]

The Role of BRCA1 and BRCA2 Gene Mutations in Advanced Prostate Cancer

Sure, we need more research about prostate cancer, but fortunately we also gain from research into other cancers. The commonly referred to breast cancer genes, BRCA1 and BRCA2 might also increase a man’s risk for developing an aggressive strain of prostate cancer. According to a report in Reuters, men with prostate cancer who also carry [...]

Gabapentin to Treat Hot Flashes

I suffered with significant hot flashes when I was on androgen deprivation therapy (ADT). I experienced between seven to 15 flashes in a twenty-four hour period. Often the flashes were accompanied with breathing difficulties and fatigue. My quality of life was significantly negatively affected. The flashes were significant enough to require that I occasionally change [...]

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