Using Denosumab (Xgeva) To Combat Skeletal Complications in Prostate Cancer

Xgeva is a monoclonal antibody that inactivates RANKL, a protein that enhances osteoclast activity and survival. By inhibiting RANKL, Xgeva prevents skeletal-related events in men with bone metastasis from prostate cancer. Under no circumstances should a man who also has multiple myeloma use Xgeva. There have been studies that compared Xgeva to zolendronic acid (Zometa). [...]

On The Horizon- MRI Guided Ultrasound Ablation of Prostate Cancer Tumors

In 1999 there was a new company started, InSightec, when GE Healthcare and Elbit Medical imaging joined their technologies to develop and manufacture non-invasive magnetic resonance (MRI) guided focused ultrasound technologies. The company has been in the process of developing a system that combines MRIs with ultrasound to non-surgically destroy fibroids and tumors. The company [...]

Two New Sites Available for Early Access to Alpharadin

There are now two new, additional sites added to the Early Access Trial of the investigational treatment known as Radium-233 or Alpharadin for men with castrate resistant prostate cancer with multiple bone metastases. This post contains the most up to date and accurate information, the clinical trials.gov site is NOT currently accurate. Additionally, there are [...]

Now an Early Access Site for Alpharedin Opens in New York

The Early Access Committee on which Malecare sits has been successful in adding an additional site in Long Island, New York to the Early Access Trial of Radium-233 Chloride (Alpharedin) for men with advanced prostate cancer who are castrate resistant and have at least two (2) bone metastases. If you are interested in this trial [...]

The FDA Approves a New Non-Invasive, Non-Ionizing Radiation Therapy to Treat Pain from Bone Metastases

The big news from yesterday is that the Food and Drug Administration (FDA) has approved a MRI-guided, focused ultrasound therapy for the treatment of bone pain associated with metastatic advanced prostate cancer. In a media release written by InSight, an Israeli company states that its ExAblate® MRI-guided, focused ultrasound technology is indicated to treat pain [...]

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