Hormone Therapy - malecare.org

Degarelix Proves to be the Superior Hormone Deprivation Treatment (ADT) for Men with Advanced Prostate Cancer

Based on six recent retrospective analyses comparing the gonadotropin-releasing hormone (GnRH) antagonist degarelix against the traditional luteinizing hormone-releasing hormone (LHRH) agonists (i.e. Zoladex, Lupron etc.) men with advanced prostate cancer experienced improved disease control, fewer instances of urinary infections, and a lower risk of cardiovascular events. The six analyses compared data from randomized trials that [...]

By Malecare|2017-10-19T10:49:17-04:00November 5th, 2013|Advanced Prostate Cancer, Drugs & Treatments, Firmagon (degarelix), Hormone Therapy, Research, Uncategorized, Understanding APC|2 Comments

Bone Disease in Men with Prostate Cancer Needs Constant Monitoring

The number of cancer survivors is increasing, soon to be as many of 13 million of us in the world! Bones are often affected in cancer survivors, usually a result of bone metastases, or of anti-cancer therapies which can contribute to bone loss and fragility. Bone disease in cancer survivors can result both from the [...]

By Malecare|2013-11-04T20:25:00-05:00November 4th, 2013|Advanced Prostate Cancer, bisphosphonates, Bone Metastases, Bone Mineral Density, denosumab - Xgeva, Drugs & Treatments, General Information, Hormone Therapy, Quality of Life, Uncategorized, Understanding APC, Zometa|0 Comments

Oligometastatic Prostate Cancer – Still Curable So Be Vigilant

It is generally agreed that prostate cancer which is still 100% confined to the prostate gland is curable using local therapies like radiation or surgery, but when it has left the prostate gland and becomes metastatic it is no longer curable. Treatment for metastatic prostate cancer is intended to make the prostate cancer a chronic [...]

By Malecare|2017-10-19T10:49:23-04:00October 9th, 2013|Advanced Prostate Cancer, Bio Chemical Recurrence, Bone Metastases, Drugs & Treatments, General Information, Hormone Therapy, oligometastic, Uncategorized, Understanding APC|7 Comments

The Differences in Ketoconazole & Abiraterone (Zytiga)

Zytiga (abiraterone acetate) and Ketoconazole (keto) are both widely used in prostate cancer therapy to treat men with advanced prostate cancer. They both have a common mechanism of action, they both work by inhibiting the enzyme CYP17 that is responsible for androgen biosynthesis (creation). Inhibiting CYP17 lowers testosterone levels, which results in prostate cancer tumor regression. Because [...]

By Malecare|2013-09-26T17:23:39-04:00September 26th, 2013|2nd line hormone therapy, abiraterone acetate, Advanced Prostate Cancer, Drugs & Treatments, General Information, Hormone Therapy, ketoconazole, Uncategorized, Understanding APC, Zytiga|0 Comments

Metastasis-Free Survival Is A Possible Biomarker for Overall Survival

Researchers at Johns Hopkins has concluded that metastasis-free survival appeared to independently predictor of overall survival (OS) in men with recurrent prostate cancer who underwent androgen deprivation therapy (ADT) after developing metastases. Men with biochemically recurrent prostate cancer (PSA only) tend to survive for long periods so the FDA gold standard for clinical trial endpoint [...]

By Malecare|2020-02-04T11:49:50-05:00September 4th, 2013|Advanced Prostate Cancer, Bio Chemical Recurrence, biomarkers, bisphosphonates, Clinical Trials, Clinical Trials, Drugs & Treatments, enzalutamide, Hormone Therapy, Research, Start A Cure, Uncategorized, Understanding APC, Xtandi, Zytiga|0 Comments