Ketoconazole – A Second Line Hormone Therapy (Part 1 of a Series of Posts on Second Line Hormone Therapy)

At some point in the progression of advanced prostate cancer the usual initial standard of care, hormone therapy (ADT2 or ADT3), will fail to control the progression of the cancer. Commonly, when ADT does fail we will experience an increase in our PSA scores and often see signs of disease progression on imaging tests. For [...]

:( Taxotere Burn :(

The taxotere burn is not the hottest, latest dance sweeping the country, it is a little discussed complication that can strike a man while having chemotherapy for the treatment of prostate cancer. If the infusion equipment is not secured tightly or the vein not properly accessed and any of the taxotere is allowed to leak [...]

BRCA2 Mutation Indicates Shorter Survival in Men with Prostate Cancer

A study performed in the UK, reported in the British Journal Cancer (2010), showed that men who have a deleterious germ-line mutation in the breast cancer 2 (BRCA2) gene and who have prostate cancer do not survive as long as men with prostate cancer who are non-carriers. There have been earlier studies that have shown [...]

Advanced Prostate Cancer Teleconference Is Available On-Line

The recent teleconference I had with Dr. James Mckiernan about advanced prostate cancer is now available to listen to on-line. Many people have been asking how to hear the conference, now you can. Go to the navigation bar above On the blog) and click on the teleconference tab. To listen to the call click on [...]

Pamidronate or Zoledronic Acid – Is There A Difference In the End Results?

Pamidronate and zoledronic acid (bisphosphonates) are a mainstay in the treatment of men with advanced prostate cancer as well as for breast cancer survivors for the prevention of skeletal-related events (SREs). There have been many clinical trials comparing the efficacy and side effect profiles between pamidronate and zoledronic acid among men with advanced prostate cancer. [...]

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