Statins & Prostate Cancer – Use Caution

There have been a number of recent studies that show that statins, (cholesterol lowering medications like Lipitor) can also lower PSA and even stop the progression of localized prostate cancer from progressing. I have not been able to locate any good study that does indicate that statin medications actually stop disease progression, however I am [...]

Pomegranate and Its Role In PSA Velocity

In 2005 there was a small clinical trial performed at UCLA evaluating pomegranate juice and its ability to control PSA for men with prostate cancer. The trial gave 8 oz. of POM Wonderful pomegranate juice each day in men with a rising PSA post treatment (recurrent advanced prostate cancer). This trial, which was funded by [...]

Dendreon Gets FDA Approval for Extra Work Stations at their New Jersey Factory

On March 10th (my birthday) Dendreon announced that it has obtained clearance of its new work stations from the FDA. The result of this clearance is the quadrupling the output from the New Jersey factory where it makes sipuleucel-T (Provenge). When Dendreon obtained FDA clearance in April of 2010, it had extremely limited manufacturing capabilities [...]

New Phase 2 Trials For MDV3100 Begins & Another To Start Soon – On The Horizon

It was announced today that the first patient in the TERRAIN study received their first dose in the Phase 2 trial of the investigational drug MDV3100 . MDV3100 is a triple-acting oral androgen receptor antagonist that I have writing about as a drug “On The Horizon”. Triple-acting means that it blocks testosterone binding to the [...]

Study Shows that Six Months of Neoadjuvant ADT Significantly Reduces Mortality in Locally Advanced Prostate Cancer

Researchers from the Trans-Tasman Radiation Oncology Group 96.01 trial study (TROG 96.01) concluded that six months of treatment with neoadjuvant androgen deprivation combined with radiation reduced the risk for disease-specific death by 49% in men with locally advanced prostate cancer. […]

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