ADT and Hot Flashes

Did you have androgen deprivation therapy (ADT)? If you have you probably experienced hot flashes. Up to 80% of men treated with ADT for prostate cancer will experience hot flashes, ranging from very mild to very severe. Along with hot flashes many of us will also have insomnia, fatigue, irritability and a host of other [...]

Exisulind On The Horizon

A study which was funded by Cell Pathways Inc., developer of the drug Exisulind, suggest that Exisulind may delay disease progression in men with recurrent prostate cancer according to Dr. Erik Goluboff, Assistant Professor of Urology at Columbia University College of Physicians & Surgeons, Director of Urology at The Allen Pavilion of New York-Presbyterian Hospital, [...]

Radiation Plus Hormone Therapy Cuts Prostate Cancer Mortality by 50% in men with Locally Advanced Disease

Investigators have reported, at the American Society for Therapeutic Radiation and Oncology (ASTRO) 50th Annual Meeting, that when radiation is added to anti-androgen therapy (ADT), survival rates are increased by 50% in men receiving only ADT. "This randomized trial is the first to show that men with locally advanced prostate cancer will survive substantially longer [...]

Procrit To Counter Anemia With ADT & Chemotherapy

It is common knowledge that androgens play a role in the production of red blood cells. The lack of androgens cause the hematocrit (proportion of blood volume that is occupied by red blood cells) level to fall in most men with prostate cancer who are on a hormone blockade. About 10% of men on a [...]

Docetaxel-Based Chemotherapy in Elderly Patients (Age 75 and Older) with Castration-Resistant Prostate Cancer Is Viable

There have been very few studies on the patterns of care and outcome of elderly (over 75 years) survivors with androgen independent prostate cancer (AIPC) who have been treated with docetaxel (Taxotere). The records of 175 French men with AIPC, over the age of 75 years, were retrospectively examined. All of the men were treated [...]

Massage Therapy- Pain Relief and Mood Control

According to a recent study in the Sept. 16 "Annals of Internal Medicine"; survivors coping with advanced cancer receive some relief from pain and depression from massage therapy. The researchers found that survivors who received massage from a licensed, specially trained therapist reported greater improvements in pain and mood symptoms than did people who received [...]

Pain – There Is No Reason To Be In Pain

Taking charge of your medical care not only might improve your survival, but it could also improve your life. According to a study in the September 1 issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of the American Society for Therapeutic Radiology and Oncology pain is the most common symptom of cancer, [...]

A New Phase II Trial for Men with Androgen Independent Prostate Cancer After the Failure of Chemotherapy

Once we develop metastatic androgen-independent prostate cancer and experience disease progression after receiving docetaxel-based chemotherapy we have no approved treatment options. We have hit the proverbial wall! In the process of attempting to develop additional treatments, ImClone Systems Inc. (NASDAQ: IMCL), announced the beginning of a Phase II clinical trial for men with advanced prostate [...]

Why ADT Ultimately Fails

Hair on a man's head offers clues about versatility of a molecule central to Advanced Prostate Cancer. Once again, those of us fighting advanced and recurrent prostate cancer are confronted with contradictory and confusing information. The usual first line treatment for advanced prostate cancer is hormone therapy (ADT). We all know that ADT is short [...]

Caution, Avoid Grapefruit And Other Juices When Taking Certain Drugs

We all know, or at have heard, that drinking grapefruit juice can increase the absorption of certain oral drugs. The result of the increased levels of absorption is the possibility that normal doses of drugs become toxic overdoses. At the 236th National Meeting of the American Chemical Society there was a presentation that provided new [...]

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