ONE PERSON’S EXPERIENCE WITH PROVENGE

Malecare has an on-line support group for men with advanced prostate cancer; their loved ones and caretakers. Today, there was a post on the support group where one of the participants shared their recent experience with Provenge, including some very specific recommendations for anyone else thinking of having the treatment. You can join us by [...]

Zoledronic Acid Shows Improved Clinical Outcomes When Administered Prior to Bone Pain in Men with Advanced Prostate Cancer

According to the FDA approval label, zoledronic acid (Zometa) should be administered to men with advanced prostate cancer once they have failed one hormone therapy type, in other words, once the cancer has become castrate resistant. Researchers at the Centre Hospitalier de i’Université de Montréal, Hôpital Notre-Dame, Montréal, Quebec, Canada evaluated the effect of zoledronic [...]

Denosumab delays the Spread of Prostate Cancer to the Bones, But it Doesn’t Extend Life!

Results from a recent clinical trial indicate that denosumab delayed the spread of prostate cancer metastases bones, however it did not prolong the lives of men. […]

Prostate Cancer Treatment Linked to An Increased Risk of Developing Colon Cancer

What is the primary treatment for men with advanced prostate cancer? We all know the answer, it is hormone therapy. Almost without exception, when we get diagnosed, we are put on to hormone therapy (ADT). ADT makes us feel terribly, it affects our stamina, our memory, our attention span, gives us hot flashes and weakens [...]

Malecare’s Advanced Prostate Cancer Program

Malecare is pleased to announce several new enhancements to our Advanced Prostate Cancer Program as well as the release of our new Advanced Prostate Cancer Kit which includes our newest publication: RECURRENT PROSTATE CANCER A Working Document for Men with Recurrent Prostate Cancer For many years, Malecare has been the leader in the fight against [...]

Xgeya (denosumb) Approved To Protect Bones In Men With Metastatic Prostate Cancer

This has been an interesting year as men with advanced prostate cancer have seen three different drugs approved. Considering that the prior six years did not have any new drug approvals, this has been a stellar year. First we had Provenge approved, then came Jevtana and now we have added to the list Xgeya (denosumb). [...]

A Survival Advantage – Is It Worth It and What Does It Mean? When Economics Interface with Survival

In order to get FDA approval, drugs must first go through a clinical trial that demonstrates that they offer a better treatment result than the current standard of care. In some instances the better result can be a demonstration that the investigational drug provides an advantage which is only palliative (as Mitoxantrone does for advance [...]

On The Horizon- XL 184 Shows Remarkable and Surprising Results In A Small & Early Trial

Although some people have called it intriguing,  a new “On The Horizon” drug, XL-184, is still very early in its testing.  What makes LX184 intriguing is the just released results from a conference in Berlin. In very early testing, 19 of 20 men in a phase I trial showed an improvement in their scans used [...]

Out On the Limb – Predicting the CME Decision on Provenge

Today, I spent most of the day listening to the CME (Medicare & Medicaid) hearing on Provenge. CME does not have to abide to the decisions of the advisory committee, so like we experienced with the FDA Advisory Committees we will have to wait and see what will eventually become the policy for reimbursement. I [...]

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