Side Effects of Xofigo – Are They Significant?

The following post is actually a response to a listserve issue over the side effects of Xofigo. I decided to post my response here to avoid the limit of lines allowed on the listserve and because I feel that it is also of interest to my regular readers of this blog. My response is using [...]

Testosterone Therapy for Prostate Cancer: Feeling Better while Defeating Cancer

Although there are now many new treatments for advanced prostate cancer, hormone therapy (ADT) has remained the standard of care for the last 70 years. While hormone therapy can provide pain relief, it is never curative. Long-term hormone therapy produces decreased quality of life. Men treated with hormone therapy have weight gain, experience impotence, decreased [...]

One Third of All Cancer Survivors Fail to Have any Conversations with their Healthcare Providers about their Psychosocial Issues

Not terribly surprising, but recent research shows that less than one-third of all cancer survivors of adult cancers in the United States ever had conversations with their healthcare providers about their psychosocial needs. The latest study showing this was published in the Journal of Clinical Oncology.1 This study was a large population-based study of 1777 [...]

Understanding & Treating Radiation Proctitis Resulting from Prostate Cancer Treatment

One of the more common side effects of primary prostate cancer treatment with any form of x-ray or ionizing radiation is known as radiation proctitis and the related radiation colitis. Radiation proctitis is inflammation and damage to surrounding organs and tissue caused by stray radiation. Radiation proctitis most commonly occurs after treatment for many different [...]

Takeda Un-blinds & Halts the Phase 3 Study of Orteronel in Men with mCRPC That Progressed Post-Chemotherapy

A press release made yesterday brought some bad news to the advanced prostate cancer community. Takeda Pharmaceutical Company Limited (“Takeda”) announced that it has un-blinded and stopped the ELM-PC 5 Phase 3 study (C21005) of orteronel plus prednisone compared to placebo plus prednisone in patients with metastatic, castration- resistant prostate cancer (mCRPC) that had progressed [...]

Go to Top