Malecare’s Advanced Prostate Cancer Program

Malecare is pleased to announce several new enhancements to our Advanced Prostate Cancer Program as well as the release of our new Advanced Prostate Cancer Kit which includes our newest publication: RECURRENT PROSTATE CANCER A Working Document for Men with Recurrent Prostate Cancer For many years, Malecare has been the leader in the fight against [...]

On The Horizon- New Prostate Cancer Imaging Shows Real Time Tumor Metabolism

Researchers at University of California at San Francisco (UCSF) and GE Healthcare have developed a new technology that appears to rapidly assess the presence and aggressiveness of prostate tumors in real time, by imaging the tumor’s metabolism. […]

A Survival Advantage – Is It Worth It and What Does It Mean? When Economics Interface with Survival

In order to get FDA approval, drugs must first go through a clinical trial that demonstrates that they offer a better treatment result than the current standard of care. In some instances the better result can be a demonstration that the investigational drug provides an advantage which is only palliative (as Mitoxantrone does for advance [...]

On The Horizon- XL 184 Shows Remarkable and Surprising Results In A Small & Early Trial

Although some people have called it intriguing,  a new “On The Horizon” drug, XL-184, is still very early in its testing.  What makes LX184 intriguing is the just released results from a conference in Berlin. In very early testing, 19 of 20 men in a phase I trial showed an improvement in their scans used [...]

Radiation Plus Hormone Therapy Increases Survival

  Prostate cancer patients who are treated with a combination of hormone therapy and radiation have a substantially improved chance of survival compared to patients who do not receive radiation, according to interim results of the largest randomized study of its kind presented at the plenary session, November 1, 2010, at the 52nd Annual Meeting [...]

Surgical Technique Provides Good Results for Men with Spine Fractures Resulting from Metastatic Cancer

Many men with metastatic prostate cancer will suffer compression fractures in their spine. Since the spine is one of the most common sites for metastatic spread of the disease, the vertebrae often become brittle and at a very high risk for fractures. Hormone therapy and radiation therapy can also have a weakening effect on bone [...]

Sodium Clodronate Improves Survival In Patients With Advanced Prostate Cancer But Not With Localized Disease

An article published Online First and in an upcoming edition of The Lancet Oncology reports that an oral bisphosphonate, sodium clodronate, improves overall survival in men with advanced prostate cancer. However, it does not reduce the risk of death in men with localized disease. These are the final results of the MRC PR05 and MRC [...]

FDA Questions Denosumab Safety in Advisory Meeting Documents

Just revealed in briefing documents which were released in advance of a scheduled Thursday meeting of the FDA’s Advisory Committee for Reproductive Health Drugs, which will be considering whether to recommend denosumab for approval, are significant concerns that denosumab, the investigational biologic drug for osteoporosis, may increase risk of serious infections through its activity against [...]

A New Clinical Trial of MDV3100 in Earlier Advanced Prostate Cancer

— A New Trial Marks Expanded Phase 3 Development of MDV3100 into Earlier-Stage Disease — Medivation, Inc. and Astellas Pharma Inc. today announced the launch of a second Phase 3 clinical trial of their investigational drug MDV3100.  This trial marks the expansion of the Phase 3 development of their novel, triple-acting oral androgen receptor antagonist [...]

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