Takeda Un-blinds & Halts the Phase 3 Study of Orteronel in Men with mCRPC That Progressed Post-Chemotherapy

A press release made yesterday brought some bad news to the advanced prostate cancer community. Takeda Pharmaceutical Company Limited (“Takeda”) announced that it has un-blinded and stopped the ELM-PC 5 Phase 3 study (C21005) of orteronel plus prednisone compared to placebo plus prednisone in patients with metastatic, castration- resistant prostate cancer (mCRPC) that had progressed [...]

Testosterone Therapy Produces Mixed Results in Post-Surgical Men with Prostate Cancer

Many men, after they have had a radical prostatectomy, find that their testosterone levels are low and are desirous of supplementing their testosterone. (This low level of testosterone is not a result of the surgery). One way of supplementing androgens is by transdermal testosterone-replacement therapy (TRT), but TRT also has the undesirable effect of increasing [...]

Evidence That Vitamin D3 Levels Effect Survival in Men with Stage IV Advanced Prostate Cancer

Conversations among survivors and evidence in the literature suggests that there is a positive association between serum 25-hydroxyvitamin D [25(OH)D] (vitamin D3) and survival in certain types of cancer, including advanced prostate cancer. Researchers from the Cancer Treatment Centers of America investigated the relationship between survival advantage and vitamin D3 levels in [...]

Efficacy and Safety of Enzalutamide (Xtandi) Monotherapy in Hormone-Naive Prostate Cancer (HNPC)

Xtandi is often referred to as a “super bicalutamide (Casodex).” Casodex functions as a androgen blockade, which deters testosterone from being able to interact with the prostate cancer cell and feed the growth of the cancer. There are some oncologists in the United States and the standard hormone treatment in Europe often utilizes Casodex as [...]

Sorting Out the Recent Negative News about the Role of Omega 3 Fatty Acids in the Diet & Its Relationship to Prostate Cancer

The recent news is unavoidable, Omega-3 Fatty Acids, usually used by men with heart ailments and prostate cancer is tied to a 71% increase of developing prostate cancer and that the cancer is often an aggressive prostate cancer! A prospective study by scientists at Fred Hutchinson Cancer Research Center has confirmed the link between high [...]

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