Clinical Trials & Research

Radioligand Therapy With 177Lu-PSMA-617 – A Novel Therapeutic Possibility on the Horizon in Men With Metastatic Castration Resistant Prostate Cancer.

We are seeing more and more novel therapies being developed to treat castrate resistant metastatic prostate cancer (mCRPC). One such therapy involves theranostic (individualized therapies for various diseases, and to combine diagnostic and therapeutic capabilities into a single agent) concepts using radiolabeled ligands of the prostate-specific membrane antigen (PSMA). In a recent study, designed to [...]

By Malecare|2016-04-28T16:08:19-04:00April 28th, 2016|Advanced Prostate Cancer, Clinical Trials & Research, Drugs & Treatments, On The Horizon, survival, Survival, Uncategorized|2 Comments

Understanding Prostate Cancer Clinical Trials – Types and Stages

The decision to enroll in a clinical trial should involve a discussion between the person with prostate cancer and that individual’s physician. Your participation should depend on many factors, including your motivation for enrolling in a trial, the stage of your prostate cancer, and the trials available and its phase. When you decide to enroll in a clinical [...]

By Malecare|2017-10-19T10:46:22-04:00April 26th, 2016|Advanced Prostate Cancer, Clinical Trials, Clinical Trials & Research, Uncategorized, Understanding Advanced Prostate Cancer|3 Comments

Belfast Clinical Trial Combining Two Radio-Therapies For Men With Advanced Prostate Cancer

Researchers at Queen’s University in Belfast along with the Belfast Trust are conducting a clinical trial evaluating the combination of two radiotherapy treatments, Radium 223 and Pelvic Radiation using Volumetric Modulated Arc Therapy (VMAT) in men with bone positive advanced prostate cancer. The trial, being called ADRRAD trial, involves combining androgen deprivation therapy (ADT) along [...]

By Malecare|2016-04-08T12:27:32-04:00April 8th, 2016|Advanced Prostate Cancer, Alpharadin (radium-223), Bone Metastases, Bones and Prostate Cancer, Clinical Trials, Clinical Trials & Research, Drugs & Treatments, Radiotherapy, Uncategorized, United Kingdom - England, Northern Ireland, Scotland & Wales, Xofigo|2 Comments

Real Life Issues About Abiraterone Acetate (Zytiga) Prior to Chemotherapy – Unanticipated Real-World Clinical Experience Worth Noting

Researchers in Hong Kong wanted to confirm the efficacy of abiraterone acetate (Zytiga) used prior to chemotherapy that had been shown in the trial setting. In their analysis they came up short; raising some very significant concerns about Zytiga’s efficacy when used prior to chemotherapy. They reviewed the clinical records of men with metastatic castrate [...]

By Malecare|2017-10-19T10:46:35-04:00April 1st, 2016|abiraterone acetate, Advanced Prostate Cancer, Asia, Clinical Trials & Research, Disease Progression, Drugs & Treatments, Research, Uncategorized, Understanding Advanced Prostate Cancer, Zytiga|2 Comments

DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer Phase II Results

We know that prostate cancer is a heterogeneous disease, but most of our treatments are not based on the different molecular stratification exhibited by the disease. One of the differences we do recognize in the cancer is that some of the tumors have genetic DNA-repair defects. There has been evidence that in those cancers exhibiting [...]

By Malecare|2020-02-04T11:43:17-05:00March 31st, 2016|Advanced Prostate Cancer, Clinical Trials & Research, genetics, olaparnib, PARP inhibitors, Uncategorized|0 Comments