On the Horizon- Patupilone in Patients with Metastatic Castration-Resistant Prostate Cancer who have Progressed after Docetaxel – A Phase II Study

Once we have failed docetaxel therapy (chemo therapy) we have very few options available to control advanced prostate cancer. There is a recnt report about a clinical trial using a new potential drug, Patupilone. Patupilone has shown some evidence that it exhibits a limited positive effect in the pre-clinical setting in taxane resistant models of [...]

Chemo Brain – Yes, Prostate Cancer Survivors Do Suffer From It

Today’s New York Times has published another of its fantastic articles about cancer and coping with cancer. Today’s article, written by Jane Brody, discusses chemo brain. Until a short time ago, many doctors denied that it even existed, but today it is pretty much accepted as being real. One is said to suffer from chemo [...]

C – Reactive Protein an Adverse Prognostic Marker for Men with Castration-Resistant Prostate Cancer

Many doctors believe that increased levels of C-reactive protein (CRP) is associated with adverse outcomes in men with castration-resistant prostate cancer (CRPC) treated with docetaxel. C-reactive protein is a protein found in the blood, the levels of which rise in response to inflammation in any part of the body. Traditionally measuring levels of c-reactive protein [...]

Living My Life In Three Week Cycles

Scott Goodwin has been a guest writer on this blog. He has been sharing his experiences and feelings as he continues his journey on chemotherapy. Scott is not doing as well as we all had hoped. His final paragraph says "When does the time come when a man will stop all treatments and try to [...]

Mitoxantrone Plus Prednisone – A Possible Fallback After Taxotere Failure

Men with metastatic hormone-refractory prostate cancer (mHRPC) who become docetaxel-refractory (no longer responsive to docetaxel therapy have no approved second line chemotherapy available. One could say that they have reached the proverbial brick wall. Where to go and what to do is not at all clear. Most of us do not want to just roll [...]

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