What You Need to Know About Xgeva or Denosumab

Xgeva, also known as denosumab, is an injectable medication (injected once a month subcutaneously under the skin in the doctor’s office) that is used to prevent bone fractures and spinal cord compression caused by bone metastases in breast and prostate cancer survivors. Solid tumors in the bone, which is a common site for individuals with [...]

Stress and Survival in Prostate Cancer – Looking at a Trial Using Muscle Relaxation and Guided Imagery in Anxiety Reducing Interventions in Prostate and Breast Cancer Chemotherapy

FROM this blog on September 9, 2015 ) According to Michael Jan, MD, and his collaborators at the Karolinska Institute in Stockholm, Sweden those of us who are experiencing high levels of stress need to be cautious. Their findings boil down to the fact that our stress could allow our prostate cancer to kill us. [...]

Adjuvant Radiotherapy Benefits Survival in Subsets of Men With Node-Positive Prostate Cancer

In an analysis of outcomes reported in the Journal of Clinical Oncology, men who were diagnosed with lymph node-positive prostate cancer (no bone involvement) who went on to receive targeted radiation (adjuvant radiotherapy)  enjoyed a survival benefit over those individuals who did not have this therapy. This finding was specifically for men with both low-volume [...]

Prostate Cancer Death Risk Linked to Higher Levels of Stress

Are you stressed? If you are and you have been treated for clinically localized prostate cancer you are at a 66% increased risk of dying from your prostate cancer! Research has shown that high stress levels are associated with an increased rate of prostate cancer (PCa) specific mortality among men treated for clinically localized prostate [...]

How We Know What Drugs Might Work In Combination With Each Other – Bringing The Next Big Breakthrough in Prostate Cancer Treatment

Many of the posts that I have written discussed the need for evaluating our current advanced prostate cancer drugs in both combinations and their sequencing. We have a number of new drugs, but we don’t understand how best to sequence them, or whether or not some drugs would do better and extend life by taking [...]

Avoiding Increased Colon Cancer Risk Created By Errors Made in a Colonoscopy

Having been diagnosed with prostate cancer does not make you immune to developing another cancer. Look specifically at me; I have now been diagnosed with five different, primary cancers. Not only do we remain susceptible to developing another, unrelated primary cancer, we also are at an increased risk of developing a secondary cancer that is [...]

Our New Therapies and the Development of Cross Resistance to these Drugs

Men with metastatic castrate resistant prostate cancer (mCRPC) have become fortunate over the last few years as there we now have a number of new drugs available which can extend our life and can also have some palliative effects. However, as we have more treatments being approved, we find that we are faced with a [...]

Intermittent Hormone Therapy Versus Continuous Hormone Therapy: a Meta-Analysis

Intermittent hormone therapy (IHT) as opposed to continuous hormone therapy (CHT) provides a better quality of life (QoL) for men with locally advanced prostate cancer. However, there is a debate created by a few major research protocols that have been inconclusive as to the difference in achieving the ultimate goal, survival despite prostate cancer. Researchers [...]

Chemotherapy in Very Elderly Men with Metastatic Castration-Resistant Prostate Cancer

Clinical trials for treatment of men with advanced prostate cancer often don’t include men who are considered very elderly (aged over 80 years). So, even if we know that a treatment is tolerable and effective in the average man, we can not assume that it would also be in the very elderly, especially in reference [...]

Perioperative Complications following Artificial Urinary Sphincter Placement After Prostate Cancer Surgery

Urinary incontinence post-prostatectomy is a too common complaint from men. Although the actual degree of incontinence suffered ranges from being minor, or a simple and small amount of post urination dribble, to a complete and total inability to control any urine flow, the most bothersome issues that significantly affects a man’s quality of life (QoL) [...]

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