Understanding the Result of Neuroendocrine Differentiation in Prostate Cancer

Understanding a little about the prostate gland and its biology is not only interesting, but it allows us to ask some important questions that can be very specific to our prostate cancer treatment decisions and our eventual outcomes from these decisions. It also can simply add to the confusion we all face in making the [...]

Using Low Dose Prednisone in First-Line Docetaxel Treatment Improves The Quality of Life (QoL) For Men With Prostate Cancer

Clinical trials are used to both demonstrate that a drug or treatment has efficacy (extends life or improves the quality of life). They also are used as the vehicle to obtain approval from the governmental body responsible for monitoring and approving their use. How the trial is set up will directly dictate the eventual approved [...]

Updated Analysis Confirms That Adherence To A Strict Mediterranean Diet Is Correlated To Longer Cancer Survival For Many Cancers, Including Prostate Cancer

Go to any support group meeting and you are almost sure to hear someone, usually a new member of the group, ask about what they might do to lower their risk of having their prostate cancer progress or even lower their risk of dying from the prostate cancer. Among the common answer to this question [...]

How Long Should We Follow-Up Clinical Trial Subjects – Maybe For The Rest Of Their Life

So, you are a hero and have decided to participate in a clinical trial. We all are deeply in your debt, so I want to start out and extend to you a very big thank you. Making that decision to participate in a clinical trial isn’t an easy decision for anyone. Participating in a trial [...]

Understanding How To Avoid The Pitfalls of Dr. Google

Today the vast majority of us have access to a computer as well as the Internet. Thanks to powerful search engines we all have easy access to the world, including to an explosion of information about our health. The fact that you are reading this blog is the best example I could offer. However, in [...]

The Role of PSA Kinetics in Men with Advanced Prostate Cancer

For men with metastatic prostate cancer, understanding ones prostate specific antigen (PSA) kinetics is important.  Despite the issues we hear  surrounding the PSA, it is still the best measure you have in aiding you in the assessing your possible outcome prognosis.  PSA kinetics also are a potential surrogate marker for  clinical trial results. In most [...]

By |2017-10-19T10:46:54-04:00October 14th, 2015|Advanced Prostate Cancer, Uncategorized|0 Comments

Teva Launches A Generic Version of Dutasteride (Avodart)

Teva Pharmaceutical Industries has received approval and launched, in the United States, a generic version of the Avodart (dutasteride) capsules at the 0.5 mg dose. Avodart, 5-alpha reductase inhibitor, is FDA approved for the treatment of men with benign prostate hyperplasia (an enlarged prostate gland), however, although not approved; men often use it as a [...]

Understanding the Current Complications In Conducting Prostate Cancer Clinical Trials

There are many trials and tribulations facing new drug approvals for men with prostate cancer. This is particularly true for men the drugs that are designed to fight metastatic castration-resistant prostate cancer (mCRPC) because of the many new treatments, all with life extending ability,  that we now have available to use. The good news is [...]

The Role of Sleep Disturbance On Prostate Cancer Risk and Progression

I stumbled upon a fascinating piece of research from Iceland that looked at the role of Circadian Disruption in Prostate Cancer Development. Knowing my own very poor sleeping patterns and having heard many other men with advanced prostate cancer complaining about very similar experiences it peaked my interest. The researchers pointed out that there have [...]

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