Early Hormone Therapy Delays Disease Progression in Advanced Prostate Cancer

Despite the fact that we have had good research for well over 15 years that show that early hormone therapy increases over all survival, some doctors still insist on delaying the start of hormone therapy. A UK randomized trial done in 1997 demonstrated a slight impact of immediate versus deferred hormone suppression in advanced prostate [...]

The New Yorker Magazine Publishes A Great Article on Immunotherapy

For those who might be interested in the April 23, 2012 edition of The New Yorker Magazine, Jerome Groopman has written an excellent article on the history and current state of Immunotherapy. The article is entitled "The T-Cell Army" and it is on page 24. Not only does the article review the history (going all [...]

From 2012 AACR Meeting – Resveratrol Effects Prostate Cancer Cells

Resveratrol (3,4’-trihydroxystilbene) is a natural product that can be found in significant concentrations food products like red wine, peanuts, walnuts etc. There have been some evidence that indicates that resveratrol has anti-tumorigenic activity, including in prostate cancer tumors. The precise mechanism associated with resveratrol-induced SIRT1 activation and cancer cell growth inhibition remains unclear, but we [...]

From the 2012 AACR Meeting – Pomegranate components modulate distinct pathways in prostate cancer cells

Pomegranate juice has long been in the folklore of prostate cancer survivors. Many of us use it with the goal of controlling our PSA. Most of the research evaluating the ability of pomegranate juice to control PSA has been funded by the juice manufacturers and must be looked at with skepticism. Dr. Radha Munagala and [...]

From the 2012 AACR Meeting – Systemic Inflammation and Survival in Men with Prostate Cancer: Evidence from the Glasgow Inflammation Outcome Study.

I met with Dr. Kashif Shafique of the University of Glasgow who was the senior author of a research poster presented at the meeting. He and his colleagues look at the relationship between systemic inflammation and prostate cancer survival. Since there is some evidence that pre-treatment of systemic inflammation in men may be associated with [...]

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