FDA Perspective on Developing Novel Combination Therapies – What We Need

Increasingly it has become obvious to me and to many other individuals that our current drug approval and development process has a basic flaw. If you go to research conferences you quickly learn that there is probably no magic bullet to stop any type of cancer, including advanced prostate cancer. Current drug development focuses on [...]

Study Results Provide Evidence for First-Line Use of Firmagon (degarelix) in Advanced Prostate Cancer

Firmagon, the newly FDA approved gonadotropin-releasing hormone (GnRH) receptor blocker should perhaps be considered as a better alternative to the traditionally used ADT drugs like lupron and zoladex (GnRH agonists) which are the current standard of care. Recent data released from the ongoing five-year Firmagon (degarelix) extension study (CS21a) has demonstrated the long term efficacy [...]

Zoledronic Acid Also Induces Cell Death in Human Prostate Cancer Cells

Bisphosphonates, specifically Zometa, is commonly used in the treatment of men with advanced prostate cancer. Zometa is used to treat and protect bones from developing fractures. Bisphosphonates are potent inhibitors of bone resorption. Additionally, in vitro studies show that zolendronic acid also inhibits prostate cancer cell growth by activating apoptosis (A form of cell death [...]

YOU CAN WIN

For some reason Charlie Sheen thinks he is winning. It's one of his catch phrases after all. Sure he's rich and famous but he's also fired, and kind of a jerk. Sadly he's in denial about his seriously deep issues. In my book he's losing. He's losing big. He's a dad and he needs to [...]

By |2020-02-04T10:47:46-05:00March 22nd, 2011|LIFE, UNSOLICITED ADVICE & SUPPORT|3 Comments
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