At the AUA Meeting – Does Provenge Provide Better Survival Numbers?

The recent AUA meetings in Atlanta had a number of interesting abstracts presented that concern men with advanced prostate cancer. Some of the more interesting abstracts were look back analysis of sipuleucel-T (Provenge) done by consultants for Dendreon, the company who manufactures Provenge. They took the data from the al three of the phase III [...]

On the Horizon – TOK-001 (Galeterone)

Tokai, a Cambridge, MA based Pharmaceutical company, just presented a promising set of Phase I data pointing to the early efficacy of its "triple whammy" pill for castration-resistant prostate cancer, TOK-001 or galeterone. In their phase 1 trial the PSA levels in about half of the 49 men in the dose-ranging study declined 30% or [...]

Zytiga – When Should We Discontinue Using It?

I have had a number of recent conversations with men with advanced prostate cancer who have been taking Abiraterone Acetate (Zytiga). The question that comes up in regular conversation is about knowing when Zytiga has stopped working or when Zytiga should be discontinued. All the real guidance we have to answer this question comes from [...]

A New Genetic Technique Predicts Prostate Cancer Relapse

According to a study published online May 9 in The American Journal of Pathology copy number variations (CNV) in both malignant and benign prostate tissue is predictive of prostate cancer relapse. The research performed at the University of Pittsburgh School of Medicine by Yan P. Yu, M.D. and colleagues evaluated whether CNV of the genomes [...]

The U.S. Preventive Services Task Force (USPSTF) Down Grades PSA Testing

Today, the U.S. Preventive Services Task Force (USPSTF) posted its prostate cancer screening final recommendation statement. The following letter was received by anyone who posted a public comment: The USPSTF is committed to making the recommendations process clear and transparent and we are able to achieve that by keeping the public fully informed throughout the [...]

Go to Top