On the Horizon: Cabozantinib (XL184) Phase II Trial in Men with Castrate Resistant Prostate Cancer

We are again looking at a potentially new block buster drug to treat men with advanced prostate cancer whose cancer has become castrate resistant. This potential drug seems to have clinical activity in both soft tissue and bone mets. This investigational drug is called Cabozantinib (XL184). It is a tyrosine kinase inhibitor with activity against [...]

Managing Nausea & Increasing Appetite During Treatment – It’s Important

A very common side effect of any cancer treatment including chemotherapy (docetaxil for men with advanced prostate cancer) and radiation is nausea. In addition to feelings of nausea many men also experience a feeling of fullness, a change in the way foods taste and strong heartburn. If you have this experience let your doctor know [...]

Stat5 as a Potential Biomarker for a Prostate Cancer Recurrence Post Surgery

Once you have had primary treatment for prostate cancer you must continue to actively monitor your PSA until you die. There is no cure; at least you should never assume that you have been cured because 1/3 of all men who have treatment will have a recurrence. What treatment you have does not matter, statistically [...]

Do We Now Need To Question the Research Published in the NEJM?

A very interesting article appeared in the Saturday, November 24, 2012 edition of the Washington Post. According to the article The New England Journal of Medicine which is among the most prestigious medical journal in the world regularly features articles over which pharmaceutical companies and their employees exert significant influence. The problem is simple, over [...]

ADT and Estradiol Therapy Modify Memory in Men being Treated for Prostate Cancer

I just cannot remember where I put my keys. What is my home telephone number? What is his name, you know the guy I sit next to everyday in the office? Sound familiar, maybe because you are on hormone deprivation therapy (ADT) to treat your advanced prostate cancer. This can explain why your normally intact [...]

Go to Top