It is common knowledge that men with metastatic castration-resistant prostate cancer (CRPC) don’t all have the same disease. There are many different types or flavors of prostate cancer. These differences are involved in the genetic structure of the cancer cell its self. Some prostate cancers have mutations in the DNA repair genes (genes whose job [...]
Today most doctors rely on their personal evaluation or objective response criteria (OR) of a man to know when docetaxel chemotherapy has stopped working. The earlier this determination can be accurately made the quicker an alternative treatment can e put into place. Personal evaluations without any validated tools are unreliable and never consistent among doctors. [...]
There have been prior studies that have shown that the generic and inexpensive drug Metformin (used to treat diabetes) could be repurposed and used to decrease the risk of developing prostate cancer as well as to treat prostate cancer. Previous studies suggested that metformin is associated with decreased risk of cancer; however, results specifically addressing [...]
Radium-223 dichloride (Xofigo) has been approved as an intravenous radiotherapy for men with castration-resistant prostate cancer (CRPC) who have multiple osseous (bone) metastases. Most often, it is used in men who have too many metastases to treat with spot radiation. Xofigo works by mimicking calcium that is attracted to bones. To be successful the drug [...]
Malecare has been an active and early member of the Defense Health Research Consortium. The consortium currently consists of 47 different organizations, which educate and advocate for research Department of Defense funding for multiple different diseases and syndromes. The consortium’s goal is to lobby Congress to continue to and to expand support for the Department [...]