About Malecare

Malecare is the world's leading men's cancer support and advocacy nonprofit organization.

A New Trial Combining Provenge with A New Investigational Treatment to Enhance Survival

I have written much about the need to begin studies of both timing and combining of the many new treatments we have recently developed for the treatment of advanced prostate cancer. With the FDA approval of Provenge, Zytiga, Jevtana, Xtandi and hopefully in the near future Radium-223 Dichloride (Alpharadin) we have many new treatment options [...]

The Literature on Androgen Deprivation Therapy (ADT) Has a Systemic Bias Causing Poor Clinical Practice In Men with Advanced Prostate Cancer

We all know that LHRH agonists are used for androgen deprivation therapy (ADT) cause a tremendous number of side effects, but it is not uncommon for our doctors to never discuss these potential side effects with us prior to starting therapy. Additionally, doctors neglect to offer alternative therapies that might accomplish the same results (like [...]

On the Horizon: Cabozantinib (XL184) Phase II Trial in Men with Castrate Resistant Prostate Cancer

We are again looking at a potentially new block buster drug to treat men with advanced prostate cancer whose cancer has become castrate resistant. This potential drug seems to have clinical activity in both soft tissue and bone mets. This investigational drug is called Cabozantinib (XL184). It is a tyrosine kinase inhibitor with activity against [...]

Managing Nausea & Increasing Appetite During Treatment – It’s Important

A very common side effect of any cancer treatment including chemotherapy (docetaxil for men with advanced prostate cancer) and radiation is nausea. In addition to feelings of nausea many men also experience a feeling of fullness, a change in the way foods taste and strong heartburn. If you have this experience let your doctor know [...]

Stat5 as a Potential Biomarker for a Prostate Cancer Recurrence Post Surgery

Once you have had primary treatment for prostate cancer you must continue to actively monitor your PSA until you die. There is no cure; at least you should never assume that you have been cured because 1/3 of all men who have treatment will have a recurrence. What treatment you have does not matter, statistically [...]

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