About Malecare

Malecare is the world's leading men's cancer support and advocacy nonprofit organization.

Zoldronic Acid Used At The Beginning of ADT Can Be Protective Against SREs

It has been accepted that Zoledronic acid (ZA)(Zometa) reduces the onset risk of skeletal-related events (SRE) caused by bone metastasis in prostate cancer as well as improving their quality of life (QOL). ZA has become a standard supportive therapy for men with prostate cancer who have bone metastasis. However, there is an issue which I [...]

By |2017-10-19T10:48:34-04:00February 20th, 2014|Advanced Prostate Cancer, bisphosphonates, Uncategorized|0 Comments

Malecare’s New Advanced Prostate Cancer Newsletter – Only Actionable Items To Live A Happier & Longer Life

Malecare has recently launched a newsletter specifically about advanced, metastatic prostate cancer. This is the only Newsletter in publication that is dedicated exclusively to advanced prostate cancer. Everything in the newsletter is about advanced prostate cancer and every article is actionable by you. The Newsletter is about things that you can use today to improve [...]

By |2017-10-19T10:48:34-04:00February 18th, 2014|Advanced Prostate Cancer, Uncategorized, Understanding APC|1 Comment

A Beautiful Caregiver Tells Her Real Story In Dealing with Her Husband’s Prostate Cancer

As I have said before, the true unsung heroes of our fight against advanced prostate cancer are our caretakers. Our caretakers are our saints, they help educate us, they advocate for us, they shield us and they make us as complete as we can possibly be. They improve our lives and help us get through [...]

Can Zytiga Be Used In Men Previously Treated With Ketoconazole: A Prospective Phase II Study

Some men with advanced prostate cancer have been given the antifungal treatment Ketoconazole (Keto) as a second line hormone treatment. Like Keto, this newer hormone treatment that is now available, Abiraterone acetate (AA) (Zytiga) works by inhibiting CYP17, the rate-limiting enzyme in androgen biosynthesis. The question being asked, if Keto has failed ,given its similar [...]

Xtandi Shows Activity in Men with Prostate Cancer Resistant to Chemotherapy and Zytiga

Since its FDA approval in 2011 FDA abiraterone (Zytiga) has supplanted docetaxel (chemotherapy), other than perhaps Provenge, as preferred first-line treatment for metastatic castrate-resistant prostate cancer. August 2012 saw the FDA approval of enzalutamide (Xtandi) for the treatment of castrate-resistant prostate cancer after chemotherapy. Researchers performed a retrospective chart review at a large medical oncology [...]

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