The Prostate Cancer Research Program (PCRP) of the Department of Defense, Congressionally Directed Medical Research Programs (CDMRP) has received our fiscal year 2012 (FY12) funding to support research projects in the prevention, detection, diagnosis, and treatment of Prostate Cancer. This is a critical request and it is important that prostate cancer survivors participate in research [...]
Despite the fact that we have had good research for well over 15 years that show that early hormone therapy increases over all survival, some doctors still insist on delaying the start of hormone therapy. A UK randomized trial done in 1997 demonstrated a slight impact of immediate versus deferred hormone suppression in advanced prostate [...]
For those who might be interested in the April 23, 2012 edition of The New Yorker Magazine, Jerome Groopman has written an excellent article on the history and current state of Immunotherapy. The article is entitled "The T-Cell Army" and it is on page 24. Not only does the article review the history (going all [...]
Resveratrol (3,4’-trihydroxystilbene) is a natural product that can be found in significant concentrations food products like red wine, peanuts, walnuts etc. There have been some evidence that indicates that resveratrol has anti-tumorigenic activity, including in prostate cancer tumors. The precise mechanism associated with resveratrol-induced SIRT1 activation and cancer cell growth inhibition remains unclear, but we [...]
Pomegranate juice has long been in the folklore of prostate cancer survivors. Many of us use it with the goal of controlling our PSA. Most of the research evaluating the ability of pomegranate juice to control PSA has been funded by the juice manufacturers and must be looked at with skepticism. Dr. Radha Munagala and [...]
I met with Dr. Kashif Shafique of the University of Glasgow who was the senior author of a research poster presented at the meeting. He and his colleagues look at the relationship between systemic inflammation and prostate cancer survival. Since there is some evidence that pre-treatment of systemic inflammation in men may be associated with [...]
I am interrupting the reviews of the AACR meeting to inform you of a very important piece of news. Men with advanced prostate cancer which is castrate resistant and who have 2 blaistic bone metastases may now have access to Alpharadin even though the FDA has not yet approved it in the United States! It [...]
Patient Power, a Partner Organization of Malecare, just released a Skype interview they made with me about some aspects of the recent AACR meeting in Chicago. I talk about the exciting results from the Phase II trial of Prostvac, a small phase II study of Pomegranate juice for men with prostate cancer as well as [...]
Curcumin is thought to have anti-cancer activity as well as to provide a synergistic effect with chemotherapy agents. Because of this Dr. Eloise Planchat of the Centre Jean Perrin, Division de Recherche Clinique, EA4231, Université d’Auvergne shared results from a prospective phase II study that assessed the impact of the combination of docetaxel (chemotherapy) plus [...]
From The AACR 2012 Meeting - Does Lycopene Effect Prostate Cancer? Yesterday’s post was about the themes I saw in cancer research. Starting today I will be reporting specific research items I saw at the meeting that specifically are important to men with prostate cancer. Dr. Peter Gann of the University of Illinois at Chicago [...]
