Malecare, Author at malecare.org

CapSure Showed the Association of Statin and Nonsteroidal Anti-inflammatory Drug use with Prostate Cancer All Cause Survival

In the prostate cancer world we often discuss treatment options, some approved by the FDA and some not approved. Among the treatment options bantered about are statins (3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor) and nonsteroidal anti-inflammatory drugs (NSAIDs). According to the folklore both these drugs are associated with reducing the risk of prostate cancer and improved [...]

By Malecare|2012-11-19T15:09:47-05:00November 19th, 2012|Advanced Prostate Cancer, Drugs & Treatments, Uncategorized|0 Comments

Now an Early Access Site for Alpharedin Opens in New York

The Early Access Committee on which Malecare sits has been successful in adding an additional site in Long Island, New York to the Early Access Trial of Radium-233 Chloride (Alpharedin) for men with advanced prostate cancer who are castrate resistant and have at least two (2) bone metastases. If you are interested in this trial [...]

By Malecare|2012-11-18T10:50:10-05:00November 18th, 2012|Advanced Prostate Cancer, Alpharadin (radium-223), Clinical Trials, Clinical Trials, Drugs & Treatments, Early/Expanded Access Programs, Metastases, Uncategorized, Understanding APC|0 Comments

Xtandi Today & Tomorrow

Medivation, the pharmaceutical company that owns Xtandi (formerly known as MDV-3100), the new androgen receptor antagonist to treat castrate resistant advanced prostate cancer has a number of active clinical trials, despite the fact that it has already been approved for use. The current FDA approval is specific; it has been approved for men who are [...]

By Malecare|2017-10-19T10:50:30-04:00November 16th, 2012|Advanced Prostate Cancer, Drugs & Treatments, Enzalutamide (MDV-3100), MDV3100, Uncategorized, Understanding APC, Xtandi|1 Comment

Radium-223 (Alpharedin) Improves Survival in Men with Metastatic Prostate Cancer

At the October 28 meeting of the American Society for Radiation the final data from the ALSYMPCA trial were presented. The trial evaluated radium-223 (Alpharedin) in men with castrate-resistant prostate cancer that had spread to the bones. Alpharedin is part of a class of drugs called alpha-particle emitters that targets bone metastases. The good news [...]

By Malecare|2017-10-19T10:50:31-04:00November 15th, 2012|Advanced Prostate Cancer, Alpharadin (radium-223), Clinical Trials, Clinical Trials, Drugs & Treatments, Uncategorized, Understanding APC|2 Comments

So, Where Is Your Evidence – Is Our Propensity to Believe the Folk Law Wasting our Time & Money

Having hot flashes because of hormone deprivation therapy (ADT)? All of us dealing with advanced prostate cancer will be on ADT, it is the usual first line of therapy and it will continue until we die. Men who elect to have radiation to treat prostate cancer as their primary treatment modality will often have some [...]

By Malecare|2017-10-19T10:50:31-04:00November 13th, 2012|Advanced Prostate Cancer, Diet, Diet and Supplements, Drugs & Treatments, General Information, Hormone Therapy, Prostate Ponderings, Research, Uncategorized, Understanding APC|0 Comments

How Much Does that Drug Cost? You Have to be Kidding!

How much money is a drug worth and how much money should we be willing to spend for it have been questions that have been increasingly asked by economists, doctors and cancer survivors. Last month in an Op-Ed article three doctors from Memorial Sloane Kettering Cancer Center in New York (Sloane) let the world know [...]

By Malecare|2012-11-09T10:07:27-05:00November 9th, 2012|Advanced Prostate Cancer, Advocacy, Drugs & Treatments, General Information, How We Live, Medicare/Medicaid, Uncategorized, Zaltrap (aflibercept)|2 Comments

CAM Supplements – Do They Work for Men with Advanced Prostate Cancer?

Many of us use supplements as either complementary or alternative medicines (CAMS) to treat our prostate cancer as well as advanced prostate cancer. If we interview a selection of men and ask what supplements they take there are a number of items we take that are fairly universal among us. They include pomegranate extract, green [...]

By Malecare|2020-02-04T08:58:43-05:00November 7th, 2012|Advanced Prostate Cancer, Diet and Supplements, Drugs & Treatments, How We Live, supplements, Uncategorized, Understanding APC|3 Comments

Elective Radiation of Pelvic Lymph Nodes During Salvage Radiotherapy Post Prostatectomy – Does It Work?

When facing a post prostatectomy biochemical failure (PSA only failure) the best way to treat is still not known. Preliminary data from Johns Hopkins [1] and Duke Universities[2] have recently provided some of the earliest evidence that salvage radiotherapy may prolong overall survival versus delay of intervention until time of symptomatic progression. Despite [...]

By Malecare|2017-10-19T10:50:32-04:00November 2nd, 2012|Advanced Prostate Cancer, Bio Chemical Recurrence, Clinical Trials, Clinical Trials, Drugs & Treatments, General Information, Radiotherapy, salvage therapy, Uncategorized, Understanding APC|0 Comments

Advanced Prostate Cancer Survivors On Androgen Deprivation Therapy Develop Persistent Changes in Immune Responses

I stumbled upon an abstract published at the end of February 2010 that raised a number of questions about hormone therapy (ADT) and its effect on the immune system. Coming out of the starting gate I assumed that ADT would adversely affect the immune system making us prone to falling victim to all sort of [...]

By Malecare|2012-11-01T12:36:11-04:00November 1st, 2012|Advanced Prostate Cancer, Combination Therapy, Drugs & Treatments, General Information, Hormone Therapy, Prostvac, Provenge, Uncategorized, Understanding APC|2 Comments

Genetic Predictors Of Fatigue For Men with Advanced Prostate Cancer Receiving Androgen Deprivation Therapy

The University of South Florida along with Moffitt Cancer Center has published a study in the October issue of Brain, Behavior, and Immunity which found that men with advanced prostate cancer who are on androgen deprivation therapy (ADT) are more likely to suffer from general fatigue if they also have single nucleotide polymorphisms in three [...]

By Malecare|2017-10-19T10:50:34-04:00October 30th, 2012|Advanced Prostate Cancer, Clinical Trials, Clinical Trials, Drugs & Treatments, genetics, Genomics, Uncategorized, Understanding APC|1 Comment

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