Paranoia, anger, fear, and acting out fantasies of a violent nature from men on Prostate Cancer androgen deprivation therapy are some of the reports we’ve received over the last year. Obviously, these are concerning and under-reported by the medical community. We have heard from people in our support groups, but have not heard or read of any instances from doctors. DO tell your oncologist if you or someone whom you are caring for is experiencing changes in the quality of their thoughts or verbalizations.