Error in ZYTIGA® Beginning Your Treatment Brochure
It has come to Malecare’s attention that the dosing schedule for ZYTIGA® (abiraterone acetate) is incorrectly described in the ZYTIGA® Beginning Your Treatment brochure.
Please destroy the ZYTIGA® Beginning Your Treatment brochure and the ZYTIGA® Resource Kit. It contains inaccurate dosing information.
Please ask your doctor, today, to ensure that you understand the appropriate dosing for ZYTIGA®. The recommended dose for ZYTIGA® is 1,000 mg (four 250-mg tablets) administered orally once daily It is a massive shame on JANSSEN that Malecare has found this out, indirectly. Patients, through their advocacy organizations like Malecare, should have been notified, directly. We say again, SHAME ON JANSSEN for outrageously poor patient communication! Direct any additional questions to Janssen Medical Information: 1-800-JANSSEN(1-800-526-7736), Monday–Friday 9 am–8 pm ET; Saturday and Sunday 9 am–5 pm ET.
Standard practice in the NHS (England) is for Prednisolone to be administered in a single dose of 10 mg (two tablets usually) with food once daily. The Zytiga is taken on an empty stomach. There is guidance about how long you wait after the Zytiga is taken before you have food and therefore the Prednisolone. What works for me is to take the Abiraterone when I wake – before 6.30-6.45 am and have the Prednisolone at about 8 pm with breakfast.
Sorry that should have been 8 am! I could never wait until evening fore breakfast!!!
I’m in California & have been on Zytiga since June 2014. I’m too hungry when I wake up to wait an hour before breakfast, & I don’t always want to wait 2 hours between my meals & snacks (fruit, seeds). What works for me is taking Zytiga at bedtime.
I take Prednisone with breakfast. My oncologist says there is no issue with the time between taking Zytiga & Prednisone, since they accumulate in your bloodstream.
I began with 10 mg of Prednisone. Eventually, a nurse told me that the easy bruising I was experiencing, primarily on my arms, was a Prednisone side effect. My oncologist, after consulting with a urologic oncologist trained at Univ. of California San Francisco, reduced my Prednisone to 5 mg. This did not eliminate the side effect, but made it less severe.
The timing of the Zytiga isn’t important, what is important is that when you take it your stomach should be empty. Food tends to carry more of the drug into your blood stream.
Joel