Zometa - malecare.org

Zoledronic Acid Shows Improved Clinical Outcomes When Administered Prior to Bone Pain in Men with Advanced Prostate Cancer

According to the FDA approval label, zoledronic acid (Zometa) should be administered to men with advanced prostate cancer once they have failed one hormone therapy type, in other words, once the cancer has become castrate resistant. Researchers at the Centre Hospitalier de i’Université de Montréal, Hôpital Notre-Dame, Montréal, Quebec, Canada evaluated the effect of zoledronic [...]

By Malecare|2017-10-19T10:53:24-04:00December 15th, 2010|Advanced Prostate Cancer, bisphosphonates, Drugs & Treatments, General Information, Metastases, Uncategorized, Understanding APC, Zometa|2 Comments

Xgeya (denosumb) Approved To Protect Bones In Men With Metastatic Prostate Cancer

This has been an interesting year as men with advanced prostate cancer have seen three different drugs approved. Considering that the prior six years did not have any new drug approvals, this has been a stellar year. First we had Provenge approved, then came Jevtana and now we have added to the list Xgeya (denosumb). [...]

By Malecare|2010-12-02T12:10:18-05:00December 2nd, 2010|Advanced Prostate Cancer, bisphosphonates, denosumab - Prolia, Drugs & Treatments, Metastases, Research, Uncategorized|1 Comment

FDA Questions Denosumab Safety in Advisory Meeting Documents

Just revealed in briefing documents which were released in advance of a scheduled Thursday meeting of the FDA’s Advisory Committee for Reproductive Health Drugs, which will be considering whether to recommend denosumab for approval, are significant concerns that denosumab, the investigational biologic drug for osteoporosis, may increase risk of serious infections through its activity against [...]

By Malecare|2017-10-19T10:53:39-04:00October 4th, 2010|Advanced Prostate Cancer, bisphosphonates, Clinical Trials, Clinical Trials, denosumab - Prolia, Drugs & Treatments, Uncategorized|0 Comments

Denosumab Demonstrates More Efficacy Than Zometa in Prostate Cancer Patients with Bone Metastases

A phase III study released at the ASCO meeting demonstrated that for men with bone metastases from prostate cancer, denosumab was more effective than Zometa® (zoledronic acid) at delaying or preventing bone complications such as fracture. […]

By Malecare|2017-10-19T10:53:51-04:00June 6th, 2010|Advanced Prostate Cancer, Drugs & Treatments, General Information, Metastases, Uncategorized, Understanding APC|0 Comments

Combining Radiopharmaceuticals and Bisphosphonates to Treat Bone Mets

A recent study of one man at the Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, The Netherlands combined both treatment modalities, radiopharmaceuticals and bisphosphonates, to combat bone pain caused by bone metastases. Their results were surprising. Bone-seeking radiopharmaceuticals and bisphosphonates are both an indicated treatment for men with prostate cancer when painful [...]

By Malecare|2017-10-19T10:54:41-04:00August 15th, 2009|Advanced Prostate Cancer, Bone Mineral Density, Clinical Trials, Clinical Trials, Drugs & Treatments, Metastases, On The Horizon, Uncategorized, Understanding APC|0 Comments