Men who develop bone metastases have often been viewed as having developed a significant negative change that prognosticates a negative impact on both their quality of life and on their survival. Contradicting this commonly held belief has been some research which has identified a subgroup of men with advanced prostate cancer with bone metastases who [...]
Analysis of the PREVAIL Trial showed that Enzalutamide (Xtandi) significantly increased overall survival and radiographic progression-free survival compared with placebo in men with prostate cancer who were asymptomatic and minimally symptomatic, chemotherapy-naive and who had metastatic castration-resistant prostate cancer (mCRPC). Now, an additional analysis of the data has shown the effect enzalutamide also has on [...]
We are in desperate need of validated biomarkers, which can serve as surrogates for survival. Currently, our doctors must make decisions about which drugs to use and how long to stay on these drugs without any scientific backup or consensus driven direction to their decisions. Our clinical trials for evaluating survival of potential new advanced [...]
The good news is that many more people are surviving years after a cancer diagnosis. According to a new analysis the proportion of people surviving cancer is increasing through out the United States. The analysis showed that for both men and women aged 50 to 64 who were diagnosed between 2005 to 2009 with a [...]
Before I get into the meat of today’s post about enzalutamide, I want to briefly make some personal comments about my absence from this blog. As I had mentioned I have been diagnosed with a fifth primary cancer, appendiceal cancer. It is a rare cancer, which required my having to remove my appendix, a piece [...]