survival benefit

On The Horizon – MDV3100 in Men With Advanced Prostate Cancer Study Will Be Stopped Early and MDV3100 Offered to All Participants

It was announced yesterday that the Independent Data Monitoring Committee (IDMC) has informed the the pharmaceuticals, Medivation and Astellas of positive results from a planned interim analysis of the Phase 3 AFFIRM trial of MDV3100 in men with advanced prostate cancer previously treated with chemotherapy. The monitoring committee found that MDV3100, the first androgen receptor [...]

By Malecare|2017-10-19T10:51:56-04:00November 4th, 2011|Advanced Prostate Cancer, Chemo Therapy Failure, Clinical Trials, Clinical Trials, Drugs & Treatments, MDV3100, On The Horizon, Uncategorized|1 Comment

Alpharadin Extends Life in Men with Advanced Prostate Cancer

Some more good news for those of us who are battling advanced prostate cancer, In a major breakthrough another new drug has been shown to prolong survival in patients with advanced prostate cancer. […]

By Malecare|2011-09-26T21:07:44-04:00September 26th, 2011|Advanced Prostate Cancer, Alpharadin (radium-223), Clinical Trials, Clinical Trials, Drugs & Treatments, Uncategorized, Understanding APC|4 Comments

Study Finds that Degarelix is Superior to Leuprolide

According to findings from a long term study, men with prostate cancer (PCa) who are treated with degarelix (a newly approved gonadotropin-releasing hormone receptor (GnRH) blocker) have a lower risk of PSA failure or death compared with those treated with leuprolide. […]

By Malecare|2017-10-19T10:52:24-04:00June 24th, 2011|Advanced Prostate Cancer, Clinical Trials, Clinical Trials, Drugs & Treatments, Firmagon (degarelix), Hormone Therapy, Research, Uncategorized, Understanding APC|1 Comment

Surgery Improves Survival Rates for Men with Advanced Prostate Cancer

Researchers from the Mayo Clinic recently announced results at the American Urological Association (AUA) Annual Meeting from a long-term study that indicates that surgery can improve life expectancy for men with advanced prostate cancer. Their study shows that 80% of men who have advanced prostate cancer and still choose to have surgery survive for at [...]

By Malecare|2011-05-22T12:01:53-04:00May 22nd, 2011|Advanced Prostate Cancer, AUA, Drugs & Treatments, General Information, Research, Uncategorized, Understanding APC|1 Comment

Study Shows that Six Months of Neoadjuvant ADT Significantly Reduces Mortality in Locally Advanced Prostate Cancer

Researchers from the Trans-Tasman Radiation Oncology Group 96.01 trial study (TROG 96.01) concluded that six months of treatment with neoadjuvant androgen deprivation combined with radiation reduced the risk for disease-specific death by 49% in men with locally advanced prostate cancer. […]

By Malecare|2011-03-28T13:49:05-04:00March 28th, 2011|Advanced Prostate Cancer, Clinical Trials, Clinical Trials, Drugs & Treatments, General Information, Hormone Therapy, Radiotherapy, Research, Uncategorized, Understanding APC, United Kingdom - England, Northern Ireland, Scotland & Wales|0 Comments

A phase III Trial Comparing Intermittent versus Continuous ADT for Men with PSA Progression after Radiotherapy

In prior studies with men who have had a PSA recurrence after radiotherapy (RT), intermittent androgen suppression (IAS) has been suggested to improve quality of life (QoL) but effects on survival are unknown. The researchers performed an inter-group randomized phase III trial, which compared IAS vs continuous androgen deprivation (CAD) to test overall survival (OS) [...]

By Malecare|2011-02-22T11:11:47-05:00February 22nd, 2011|Advanced Prostate Cancer, Clinical Trials, Clinical Trials, Drugs & Treatments, Hormone Therapy, Radiotherapy, Uncategorized, Understanding APC|0 Comments

Timely Use of Zoledronic Acid Provides Both Longer Hospital Free Survival and Increased Survival

A recent study conducted at the Southeast Louisiana Veterans Health Care System, New Orleans, LA, USA by the Section of Hematology and Medical Oncology, Tulane University School of Medicine, New Orleans, LA, evaluated the efficacy of the timely use of zoledronic acid (ZA) on clinical outcomes and health care utilization in men with bone-metastatic prostate [...]

By Malecare|2017-10-19T10:53:19-04:00February 4th, 2011|Advanced Prostate Cancer, bisphosphonates, Drugs & Treatments, Research, Uncategorized, Understanding APC, Zometa|3 Comments

A Survival Advantage – Is It Worth It and What Does It Mean? When Economics Interface with Survival

In order to get FDA approval, drugs must first go through a clinical trial that demonstrates that they offer a better treatment result than the current standard of care. In some instances the better result can be a demonstration that the investigational drug provides an advantage which is only palliative (as Mitoxantrone does for advance [...]

By Malecare|2017-10-19T10:53:25-04:00November 30th, 2010|Advanced Prostate Cancer, Cabazitaxel, Chemo Therapy, Clinical Trials, Clinical Trials, Drugs & Treatments, FDA, General Information, How We Live, Provenge, Research, Uncategorized, Understanding APC|0 Comments

Radiation Therapy Improves Survival Benefits for Men with Recurrent Prostate Cancer – A New Study

When I returned from the conference (see yesterday’s post) I kept seeing notices and announcements from a new retrospective study out of John;s Hopkins that showed that men with prostate cancer tumors that recur after prostate cancer surgery are three times more likely to survive their disease long term if they undergo radiotherapy within two [...]

By Malecare|2017-10-19T10:57:35-04:00June 22nd, 2008|Advanced Prostate Cancer, Drugs & Treatments, Radiotherapy, Uncategorized, Understanding APC|0 Comments