Conversations among survivors and evidence in the literature suggests that there is a positive association between serum 25-hydroxyvitamin D [25(OH)D] (vitamin D3) and survival in certain types of cancer, including advanced prostate cancer. Researchers from the Cancer Treatment Centers of America investigated the relationship between survival advantage and vitamin D3 levels in [...]
Another interesting research abstract presented at the Genitourinary Cancers Symposium in Orlando Florida this month found that men with prostate cancer who were on chemotherapy who had also received anticoagulant (blood-thinners) medications experienced improved overall survival rates compared to men who did not take anticoagulants drugs. This retrospective study involved the reviewed of the medical [...]
At the recent 2013 2013 Genitourinary Cancers Symposium there was an abstract presented that updated data from the COU-AA-302 clinical trial of Abiraterone Acetate (Zytiga) with prednisone. The updated data confirms that Zytiga with prednisone improves overall survival (OS) in men with metastatic castrate resistant prostate cancer (mCRPC) post-docetaxel therapy (chemotherapy)(Lancet Oncol 2012;13:983-92). The trial [...]
In the prostate cancer world we often discuss treatment options, some approved by the FDA and some not approved. Among the treatment options bantered about are statins (3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor) and nonsteroidal anti-inflammatory drugs (NSAIDs). According to the folklore both these drugs are associated with reducing the risk of prostate cancer and improved [...]
At the October 28 meeting of the American Society for Radiation the final data from the ALSYMPCA trial were presented. The trial evaluated radium-223 (Alpharedin) in men with castrate-resistant prostate cancer that had spread to the bones. Alpharedin is part of a class of drugs called alpha-particle emitters that targets bone metastases. The good news [...]