Bone Turnover Marker Data And Additional PSA Progression Safety Analysis For Toremifene 80 Mg Phase III ADT Clinical Trial

GTx, Inc. (Nasdaq: GTXI) has conducted a number of clinical trials using toremifene citrate in both the treatment of breast and prostate cancer. Older women and men as well as women and men being treated for both breast and prostate cancers are subject to bone loss leading to an increased risk of falls and fractures. [...]

ADT and Hot Flashes

Did you have androgen deprivation therapy (ADT)? If you have you probably experienced hot flashes. Up to 80% of men treated with ADT for prostate cancer will experience hot flashes, ranging from very mild to very severe. Along with hot flashes many of us will also have insomnia, fatigue, irritability and a host of other [...]

Radiation Plus Hormone Therapy Cuts Prostate Cancer Mortality by 50% in men with Locally Advanced Disease

Investigators have reported, at the American Society for Therapeutic Radiation and Oncology (ASTRO) 50th Annual Meeting, that when radiation is added to anti-androgen therapy (ADT), survival rates are increased by 50% in men receiving only ADT. "This randomized trial is the first to show that men with locally advanced prostate cancer will survive substantially longer [...]

Circulating Tumor Cells as a Prognostic Factor of ADT Responsiveness in Survivors With Hormone Naive Metastatic Prostate Cancer

When we make treatment decisions we never know how effective the treatment will actually be for each individual and for how long that treatment effect might last. This makes all of our treatment decisions guess work. A recent study has demonstrated that counting circulating tumor cells in the blood can be used to predict prostate [...]

Why ADT Ultimately Fails

Hair on a man's head offers clues about versatility of a molecule central to Advanced Prostate Cancer. Once again, those of us fighting advanced and recurrent prostate cancer are confronted with contradictory and confusing information. The usual first line treatment for advanced prostate cancer is hormone therapy (ADT). We all know that ADT is short [...]

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