A small phase III, randomized, double blind, placebo controlled trial of Gabapentin which looked at the Management of hot flashes in men on a hormone blockade (ADT) was recently completed and published in the March 2009 journal of the Ann of Oncology. One of the most common and bothersome side effects of a hormone blockade [...]
The occasionally discussed, but not often used, alternative hormone therapy, transdermal estrogen might be ready to soon move on to a phase III trial. A poster presentation of a phase II trial showed that transdermal estrogen patches drove down testosterone and PSA levels to a similar extent as an LHRH analog. The poster presentation was [...]
I have always assumed that treating my prostate cancer with a hormone blockade increases my risk of having a cardiovascular problem that increases my chance of death. Taking any drug is always a trade off, one benefit against the potential harms. It is a perfect risk-reward situation. However, there is some new research that makes [...]
On January 30 I had my standard blood work, which included the old reliable PSA. As I have predicted, my PSA has continued to double at the rate of 5.1 months with the velocity of 0.02 ng/ml/mo. This is a rate that is consistent with the prior doubling rates, although my oncologist has told me [...]
I suffered with significant hot flashes when I was on androgen deprivation therapy (ADT). I experienced between seven to 15 flashes in a twenty-four hour period. Often the flashes were accompanied with breathing difficulties and fatigue. My quality of life was significantly negatively affected. The flashes were significant enough to require that I occasionally change [...]