Cognitive Impairment From Luteinizing Hormone-Releasing Hormone Agonists for Prostate Cancer

When I was on an active hormone blockade (ADT2) I suffered extensively from many of the usually reported morbidity issues (negative side effects). One of the side effects I dealt with was significant cognitive impairment. I live in New York City, was born in the city and have spent most of my life in the [...]

ADT Increases Risk Factors for Diabetes, Fractures and Cardiovascular Mortality

Not a very big surprise but androgen-deprivation therapy (ADT) substantially increases the risk for cardiovascular and bone-related problems, as well as for diabetes, according to a review of the medical literature published online April 27 in the journal Cancer. At the University of Texas Health Science Center in Houston, Lockwood G. Taylor wrote a review [...]

Long-Term Effects of Intermittent Androgen Suppression on Testosterone Recovery and Bone Mineral Density: Results of a 33-Month Observational Study

A phase II trial was just completed at the University of Western Australia to investigate changes in bone mineral density (BMD) and osteoporosis in men on intermittent androgen-suppression therapy (IAST) over a period of three years. This trial, conducted at the Faculty of Medicine, University of Western Australia, Crawley, Department of Radiation Oncology, Sir Charles [...]

Sexual Behavior At Work Still A Problem

A new paper published in the Journal of Applied Psychology and co-authored by researchers from the University of Toronto’s Rotman School of Management and the University of British Columbia's Sauder School of Management concluded that sexual behavior at work creates a problem in the work place, especially morale. The study looks at sexual behavior in [...]

Denosumab Increased Bone Mineral Density in Men With Nonmetastatic Prostate Cancer

Presented at EAU on March 23, 2009 The drug Denosumab has shown itself both easy to tolerate by patients as well highly able to increases bone mineral density (BMD) when compared with placebo in men with nonmetastatic prostate cancer receiving androgen deprivation therapy (ADT). The results of this multi-centre, randomized, double-blind, placebo-controlled, phase 3 study [...]

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