Nausea and Vomiting

What causes it: Nausea (feeling sick to your stomach) and vomiting are classic side effects of chemotherapy. Not all chemo drugs cause nausea equally, but the ones often used in advanced prostate cancer (such as docetaxel) certainly can cause queasiness. Chemotherapy works by attacking rapidly dividing cells, and it can affect the cells in your gastrointestinal tract and the chemoreceptor trigger zone in your brain that controls vomiting​. This triggers those sick feelings and sometimes vomiting. Hormone therapy for prostate cancer can also cause mild nausea in some men​, especially when first starting treatment, but it’s generally less intense than chemo-induced nausea. Additionally, anxiety or pain can cause “psychological” nausea for some patients, but the most common cause is the medications themselves. It’s worth noting that modern anti-nausea medications given with chemotherapy have improved the situation a lot – many men get through chemo with minimal vomiting nowadays – but you might still experience some nausea or appetite loss on treatment days.

 

How it affects daily life: Nausea can make it difficult to eat and maintain nutrition. You may find that foods you used to enjoy now turn your stomach. During a cycle of chemotherapy (often given every 3 weeks), you might feel the most nausea in the first few days after the infusion. This can lead to loss of appetite and even weight loss if it’s prolonged​. Vomiting, if it occurs, can be exhausting and can cause dehydration. Constant nausea also saps your energy and concentration – it’s hard to go about daily activities or focus on work when you’re feeling queasy. You might become sensitive to strong smells (like cooking odors or perfume) as they could trigger a wave of nausea. Many men find that their taste changes during chemotherapy; some report a metallic taste in the mouth or that foods taste bland or “off.” This, combined with nausea, might make eating a chore rather than a pleasure. If nausea is not well-controlled, it can significantly reduce your quality of life during treatment. Thankfully, in most cases, nausea is temporary and tied to the chemo schedule (for instance, feeling sick for a few days post-infusion, then gradually improving before the next cycle).

 

Ways to manage or reduce it: Managing nausea is very important for keeping up your strength and morale. Medications: Always take the anti-nausea (antiemetic) medications your doctor prescribes around chemo time. There are several types (ondansetron, dexamethasone, aprepitant, etc.), and they are often given in combination. These can hugely reduce the risk of vomiting. If one medication isn’t enough, inform your doctor – there are many options, and it may take a couple of tries to find what works best for you. Diet and eating tips: Rather than three big meals, try small, frequent snacks throughout the day​. It’s easier to handle a little food at a time. Eat bland foods that are easy on the stomach – plain toast, crackers, rice, bananas, or clear soups. Some men find cold or room-temperature foods are better tolerated than hot foods (because strong odors from hot foods can trigger nausea)​. For example, cold chicken, cheese, or a smoothie might go down easier than a hot meal. Stay hydrated by sipping fluids throughout the day, but it might help to avoid drinking large amounts during meals (drink between meals instead)​.

This prevents overfilling your stomach. Ginger is a well-known natural remedy for nausea – you could try ginger ale (let it go flat to reduce carbonation which can bloat you), ginger tea, or ginger candies, as some patients find relief with these. Environment: Keep your surroundings calm and well-ventilated. Fresh air or a gentle breeze can help if you’re feeling queasy. Relaxation techniques like deep breathing, listening to soothing music, or meditation may ease anxiety-related nausea. After vomiting care: If you do vomit, rinse your mouth afterward to get rid of stomach acid and prevent bad taste. Wait a bit before trying to eat or drink again, and start with small sips of water or an electrolyte solution. When to contact the doctor: If you can’t keep fluids down or if nausea is very severe despite medication, let your healthcare team know immediately. They can adjust your anti-nausea regimen or give IV fluids if needed. Remember, controlling nausea is a priority – there’s no reason to “tough it out” if better relief is available. With the right combination of antiemetics and self-care, most men get through chemo with manageable nausea, and their appetite returns to normal a few days after each treatment​.