Prostate Cancer SATURN Trial, a Phase 3 Trial in Men with Metastatic Prostate Cancer

A new phase 3, registration trial has been announced by OncoGenex Pharmaceuticals, Inc. of its investigational drug custirsen sodium (OGX-011/TV-1011). The trial, for men with metastatic castrate resistant prostate cancer (mCRPC) is referred to as the Prostate Cancer SATURN Trial. This randomized, controlled, trial will include approximately 50 cancer centers and is planned to enroll [...]

Cyclophosphamide (Cytoxan®) -Another Possible 2nd Line Chemotherapy for HRPC After Docetaxil Failure

Researchers, Nelius T, Klatte T, de Riese W, Haynes A, Filleur S. from the Department of Urology, Texas Tech University Health Sciences Center, Lubbock, TX. studied the efficacy of cyclophosphamide (CP)-based metronomic chemotherapy in men who have docetaxel-resistant hormone-refractory prostate cancer (HRPC). […]

The FDA Approves Jevtana (Cabazitaxe) For Use After Chemotherapy Failure

Hot off the press- The U.S. Food and Drug Administration (FDA) has approved Sanofi-Aventis SA's new chemotherapy drug for advanced prostate cancer. The drug, Jevtana (cabazitaxe) extended by nearly 2-1/2 months the lives of men with prostate cancer tumors that resist standard treatment with hormones as well as chemotherapy. The drug will be used after [...]

The Question, When to Use A Treatment & What Drugs Should Be Combined?

The approval of Provenge has once again brought to the forefront the very important questions about the proper timing of treatments as well as the issue concerning how to combine therapies to maximize survival. We have, although there numbers are limited, different treatments that are used for the treatment of advanced prostate cancer, but we [...]

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