Statins Might Inhibit Prostate Cancer from Invading Bones

One of the more recent conversations surrounding prostate cancer treatment that we have been hearing involves the use of the anti-cholesterol drugs or statins.   The conversation, whether or not statins might be a good treatment option for men with both localized disease and as an alternative to hormone treatment (ADT) for men with advanced prostate [...]

A Surprising Biochemical Response to Ketoconazole In Post-Chemotherapy mCRPC Men When Compared to the Zytiga Trial Results

It has always been assumed that Ketoconazole, when used for the treatment of men with metastatic castration resistant prostate cancer (mCRPC), would not be as potent as abiraterone (Zytiga), but there has never been any head to head comparison to demonstrate this assumption! Ketoconazole is a less potent inhibitor of the CYP-17 enzyme, the mode [...]

Just One Year On Androgen Deprivation (ADT) Creates Significant Lipid and Glucose Metabolism Problems

It is a widely understood that androgen deprivation therapy (ADT)  causes adverse side effects and events.  Some researchers believe that the ADT-induced alterations in lipid and glucose metabolism may be race-dependent. To evaluate this concern the researchers recruited Japanese men with newly diagnosed prostate cancer who also underwent at least one year of ADT.  They [...]

Cancer Depression – No Denying It Haunts Us All

We all are subject to developing depression and prostate cancer survivors are subject to a large share of it.  Besides dealing with the everyday issues of living our life, we also are hounded by our diagnosis.   However, it is important to understand that there are everyday types of depression and what is referred to as [...]

Denosumab or Zoledronic Acid – Which is Superior for Pain Interference and Improving Quality of Life?

Men with castration-resistant prostate cancer (CRPC) and bone metastases (BM) will often have debilitating pain that impacts every aspect of their daily functioning thus significantly diminishing their quality of life (QoL). Finding the best drug or treatment to control the pain will allow men to have a more complete and fulfilling life as well as [...]

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