Can You Ever Be Re-Treated With Xofigo? Finding The Answer With A New Clinical Trial

Now that Radium-223 Dichloride (Xofigo) has been approved by the FDA for use in men with castrate resistant prostate cancer with bone metastases we will begin to see the actual treatments happening. The next question in the process that will arise is whether or not it is safe and effective to re-treat an individual with [...]

Predicting Survival in Men with Spinal Cord Compression from Metastatic Prostate Cancer

There was a recent study to investigate the predictive value of the number of extra-spinal organs involved by metastases for survival in metastatic spinal cord compression (MSCC) from prostate cancer. This was a very small study of only 95 men irradiated with 10×3 Gy for MSCC from prostate cancer. The investigators considered seven factors: Age, [...]

Hot Flash Treatments Used for Women Don’t Work in Men with Advanced Prostate Cancer on ADT

Those of us with advanced prostate cancer who have used hormone therapy (ADT) often find that we are plagued with hot flashes that are detrimental to our quality of life (QOL). I believe that hot flashes are the most common side effect complained about by men who are on ADT, in the scheme of seriousness [...]

PLATO – A New Phase 4 Clinical Trial Extending the Use of Xtandi & Combining It with Zytiga

The makers of Enzalutamide (Xtandi), Astellas Pharma US, Inc and Medivation, Inc have begun a Phase 4 clinical trial known as PLATO. The study is designed to evaluate the efficacy and safety of continued treatment with enzalutamide (Xtandi) plus abiraterone acetate (Zytiga) and prednisone as compared to treatment with Zytiga and prednisone alone in men [...]

Clinical Trials – An Alternative Method to Locate A Trial

If you are interested in participating in a clinical trial but just can not figure out how to navigate the government's clinical trial web page (www.clinicaltrials.gov)  you could call 1-800-4-CANCER for assistance.  This number will put you in touch with the National Cancer Institute's (NCI) Center for Cancer Research. The operators who answer the phone [...]

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