Developing a New Prognostic Model for in Men with First Line Chemotherapy

Current Prognostic models for overall survival (OS) for men with metastatic castration-resistant prostate cancer (mCRPC) have become dated. They don’t  adequately reflect the many new drugs used in clinical practice. To develop a relevant model data from a phase III trial of 1,050 men with mCRPC were used (Cancer and Leukemia Group B CALGB-90401 [Alliance]) was evaluated. [...]

Cancer Depression – No Denying It Haunts Us All

We all are subject to developing depression and prostate cancer survivors are subject to a large share of it.  Besides dealing with the everyday issues of living our life, we also are hounded by our diagnosis.   However, it is important to understand that there are everyday types of depression and what is referred to as [...]

Denosumab or Zoledronic Acid – Which is Superior for Pain Interference and Improving Quality of Life?

Men with castration-resistant prostate cancer (CRPC) and bone metastases (BM) will often have debilitating pain that impacts every aspect of their daily functioning thus significantly diminishing their quality of life (QoL). Finding the best drug or treatment to control the pain will allow men to have a more complete and fulfilling life as well as [...]

Understanding What Are Circulating Tumor Cells And What Is Their Role In Prostate Cancer Treatment

Circulating tumor cells (CTCs) is an area we will continue to hear more about as their importance to our understanding prostate cancer continues to increase.   CTCs show the movement of cancer cells though the body. It is believed that these CTCs are the method that cancer uses to spread through our body (metastasize). Measuring the [...]

The Ipilimumab (Yervoy) Results – A Failure that Should Not Have Been A Failure

Last October at the European Cancer Congress 2013 there was a release of data from a phase 3 study of Ipilimumab (CA 184-043) that showed that it might be effective in treating castration-resistant prostate cancer in men who have a low burden of disease; however it failed to show at the required 95% confidence level [...]

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