Baseline PSA Predicts Risk of Death from Prostate Cancer

The common question when we are diagnosed with prostate cancer is how long do I have to live? The exact same question is asked again when we discover that we have had a prostate cancer recurrence. Times have changed and so has our potential life span. In the late 1980s and early 1990s men diagnosed [...]

An Important Fact from the 2010 AUA Meeting

Findings from the Prostate, Lung, Colorectal and Ovarian (PLCO) screening trial indicate that the strongest predictors of prostate cancer-specific mortality include Gleason 7, body mass index >30, African-American race, PSA level, stage, and high co-morbidity score. Understanding how non-tumor factors affect prostate cancer-specific mortality will help identify those men who may benefit from screening and [...]

Finasteride Extends PSA Doubling Time & Reduces the Rate of PSA Increase

Finasteride, which remains a controversial drug in the treatment of men with advanced prostate cancer, prolongs the time of off-treatment in men with advanced prostate cancer when they are using intermittent androgen suppression therapy (IAD). One of the questions not yet understood is whether this results from a true increase in prostate-specific antigen (PSA) doubling [...]

An Editorial – What Has Caused the Recent Review of Provenge by the CMS

There has been a lot of questions raised about why the Centers for Medicaid and Medicare Services (CMS) has out of the clear blue, launched a review of Provenge, a review that could ultimately make Provenge unavailable to men on Medicare and Medicaid (see the post:Medicare Funding for Provenge, We Urgently Need Your HELP). There [...]

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