An alternative to standard hormone therapy (ADT) using luteinizing hormone-releasing hormone (LHRH) analogs like leuprolide (Lupron®, Eligard®), goserelin (Zoladex®), triptorelin (Trelstar®), and histrelin (Vantas®) for men with advanced prostate cancer, but often not used is estradiol (a form of estrogen). When estrogens were first used as a therapy for men with advanced prostate cancer they [...]
According to a study published in the Feb. 20 issue of the Journal of Clinical Oncology adults with cancer can experience improvements in their emotional distress levels and in their quality of life through the use of psycho-oncologic interventions, such as relaxation, individual and group psychotherapy, and psychoeducation. Hermann Faller, M.D., Ph.D., of the University [...]
We have long known that Zoledronic Acid (Zometa) decreases a man’s risk of developing skeletal-related events (SREs) in men with castration-resistant advanced prostate cancer (CRPC) and bone metastases. In a phase III study that evaluated efficacy and safety of earlier treatment with Zometa in men with advanced prostate cancer which is still castration-sensitive found that [...]
Today, I am going to make a little change in my post. Instead of discussing additional ASCO Conference abstracts of interest to men with advanced prostate cancer (I will come back to them in short order), I want to respond to the latest public outrage that has been in the media. A recent story has [...]
Ra-223 (Alpharadin)is an alpha-pharmaceutical targeting bone metastases (mets) with high-energy, short-range (< 100 ?m) alpha-particles. Currently it has been submitted to the FDA for approval, which we hope will happen by August 2013. In the phase 3, double-blind, randomized, multinational ALSYMPCA study, Ra-223 significantly improved overall survival (OS) in men with castrate resistant advanced prostate [...]