FDA: 5-Alpha-Reductase Inhibitors May Increase High-Grade Prostate Cancer Risk

There is a constant debate between both oncologist and advocates about the value and safety of 5-alpha-reductase inhibitors (Proscar and Avodart) both in the early treatment and later treatment of men with prostate cancer. In fact, I have had an on-going private debate with one very knowledgeable educator advocate over this issue. I often have [...]

ASCO 2011: Phase II Cabozantinib Trial in Patients with Advanced Solid Tumors and Bone Metastases

Data from the recent ASCO conference on a phase II study of cabozantinib (XL184) in patients with advanced solid tumors, including prostate cancer, demonstrates that the investigational treatment has activity in both bone and soft tissue. This study evaluated the efficacy and safety of cabozantinib compared to placebo in 9 different solid tumor types including [...]

Update on Potential DOD Funding for the Prostate Cancer Program

From Anthony Hardie, Madison, Wis. All: I've just gone through the full Defense Committee bill (before yesterday's markup) and the corresponding report language on the various CDMRP programs. The results are below. FY12 Defense Appropriations -- Full Committee Bill (before yesterday's markup): 1. Several programs would not be funded at all: most notably the sort [...]

Surgery Improves Survival Rates for Men with Advanced Prostate Cancer

Researchers from the Mayo Clinic recently announced results at the American Urological Association (AUA) Annual Meeting from a long-term study that indicates that surgery can improve life expectancy for men with advanced prostate cancer. Their study shows that 80% of men who have advanced prostate cancer and still choose to have surgery survive for at [...]

From the AUA – Treated Positive Surgical Margins Impact Survival

Currently the American Urologic Association is holding their annual conference. Like the ASCO and AACR conferences there are many presentations and posters given that harkens the latest in research findings for general urological topics as well as for prostate cancer. I will be reporting on a number of these findings over the next period of [...]

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