Drug Abuse Disorders Negatively Impact Advanced Prostate Cancer Treatment Results

Researchers have reported ahead of print that substance use disorders may adversely affect outcomes in men with advanced prostate cancer This conclusion was drawn from a very large study of 14,277 men with advanced prostate cancer. The study found that men with advanced prostate cancer along with a substance abuse disorder were 2.3 times more [...]

Emergency Alert- We Need to Respond – The U.S. Senate Threatens to Cut the DOD Prostate Cancer Research Program Budget

In my most humble opinion among the most vital and impactful program in the world, which supports prostate cancer research funding and prostate cancer research resources, is in trouble. It is the only government program that funds only prostate cancer research. All of its research funding mechanisms are designed to fund high risk and potentially [...]

What are the Clinical implications of Chemotherapy for Men with Advanced Prostate Cancer Under the Age of 60 years?

Yesterday’s post was about the use of chemotherapy (with docetaxel) for the treatment of men with advanced prostate cancer who were 80 years old or older. Today’s post is about the use of chemotherapy in men 60 years or younger. The research for both of these posts was performed by the same team of scientists [...]

Should Men Over the Age of 80 Years Consider Chemotherapy? *

Chemotherapy (chemo with docetaxel) has a reputation for being a difficult therapy loaded with many side effects.  I believe that this reputation is overblown given that all of our new non-chemotherapies (other than Provenge) come with their own list of significant side effects.  However, its reputation is in the minds of many, so men who [...]

Predicting Resistance to Enzalutamide and Abiraterone in Men with Metastatic Castration-Resistant Prostate Cancer (mCRPC).*

In yesterday's post I wrote about the possibility of looking for the presence of the splice variant ARV7 to determine if you would be resistant to enzalutamide (Xtandi).  Today I am going to expand on this issue and discuss an additional study that demonstrated that the presence of ARV7 in circulating tumor cells not only [...]

Go to Top