Mortality is Directly Related to Both Time to Recurrence and Risk Level of Prostate Cancer

Mortality prospects after a prostate cancer recurrences following a radical prostatectomy has always been assumed to be directly related to the early development of metastases. A study from Melbourne Australia indicates that men with low-risk prostate cancer have good mortality prospects even when they experience early biochemical recurrence. The first author of the study, Anthony [...]

On the Horizon – Cabozantinib for the Treatment of Bone Mets in Men with Advanced Prostate Cancer

According to researchers from the University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan men with advanced prostate cancer experienced significant and rapid positive effects from an investigational treatment known as cabozantinib. In a n article published online in the Journal of Clinical Oncology (Nov. 19, 2012) approximately two-thirds of men who were treated with [...]

Deciding Whether to Allow CPR in People with Advanced Cancer

It is unfortunate, but some of us will approach a time when we know that the advanced prostate cancer we have been battling has gotten the better of us and will end our life in the near future. If we are admitted into the hospital we will be asked to sign a lot of papers [...]

The Literature on Androgen Deprivation Therapy (ADT) Has a Systemic Bias Causing Poor Clinical Practice In Men with Advanced Prostate Cancer

We all know that LHRH agonists are used for androgen deprivation therapy (ADT) cause a tremendous number of side effects, but it is not uncommon for our doctors to never discuss these potential side effects with us prior to starting therapy. Additionally, doctors neglect to offer alternative therapies that might accomplish the same results (like [...]

ADT and Estradiol Therapy Modify Memory in Men being Treated for Prostate Cancer

I just cannot remember where I put my keys. What is my home telephone number? What is his name, you know the guy I sit next to everyday in the office? Sound familiar, maybe because you are on hormone deprivation therapy (ADT) to treat your advanced prostate cancer. This can explain why your normally intact [...]

So, Where Is Your Evidence – Is Our Propensity to Believe the Folk Law Wasting our Time & Money

Having hot flashes because of hormone deprivation therapy (ADT)? All of us dealing with advanced prostate cancer will be on ADT, it is the usual first line of therapy and it will continue until we die. Men who elect to have radiation to treat prostate cancer as their primary treatment modality will often have some [...]

Curcumin Might Curb the Development of Metastases in Advanced Prostate Cancer

Powdered turmeric is a common ingredient of Indian food and a substance that has been used for centuries to treat osteoarthritis and other illnesses. In March 2012 researchers from Michigan State University found that curcumin may be beneficial for people with Parkinson's disease as well as head and neck cancers. It is now thought that [...]

Brachytherapy As A Salvage Therapy for Radiotherapy Failure

Can brachytherapy be a reasonable salvage option for men with a local recurrence after the failure of initial radiotherapy for prostate cancer treatment? A recent review of the literature evaluated the use of radiation as a salvage option after the failure of local-only treatment with radiation. The results were mixed. The researchers did a PubMed [...]

A Common Advanced Prostate Cancer Emergency – Spinal Cord Compression

Spinal cord compression is not an uncommon occurrence in men with advanced prostate cancer. Bones are the most common target of advanced prostate cancer, including the spine. Sadly, there is often a delay in diagnosing spinal cord compression resulting from prostate cancer. These delays in diagnosis can influence the eventual functional outcome. Oncologists, primary care [...]

Can Tamoxifen Manage Breast Events Induced by Non-Steroidal Antiandrogens in Men with Advanced Prostate Cancer?

Many of us who are fighting advanced prostate cancer struggle with the perplexing side effects of non-steroidal antiandrogens (like Casodex). These side effects include gynecomastia (breast enlargement) and breast pain. In most cases as we use these drugs our breasts grow, become very sensitive and/or painful. In my case my breasts have grown to the [...]

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