What Is Hormone Refractory Prostate Cancer

As I have discussed many times there is very little consensus about standard definitions or treatments for prostate cancer. Go to any doctor who supplies primary treatment and ask about their erectile or incontinence rates. Then ask them how they define those rates. The results will be all over the place with no consistency among [...]

Aspirin may interfere with ADT treatment Prostate Cancer

Recent studies have raised a red flag of caution; it may not be wise also to be taking aspirin while on a hormone blockade (ADT). Recent findings show that for some men taking aspirin, which is commonly used in low daily doses for prevention of heart attack and stroke, may result in liver toxicity. Liver [...]

Bone Turnover Marker Data And Additional PSA Progression Safety Analysis For Toremifene 80 Mg Phase III ADT Clinical Trial

GTx, Inc. (Nasdaq: GTXI) has conducted a number of clinical trials using toremifene citrate in both the treatment of breast and prostate cancer. Older women and men as well as women and men being treated for both breast and prostate cancers are subject to bone loss leading to an increased risk of falls and fractures. [...]

ADT and Hot Flashes

Did you have androgen deprivation therapy (ADT)? If you have you probably experienced hot flashes. Up to 80% of men treated with ADT for prostate cancer will experience hot flashes, ranging from very mild to very severe. Along with hot flashes many of us will also have insomnia, fatigue, irritability and a host of other [...]

Radiation Plus Hormone Therapy Cuts Prostate Cancer Mortality by 50% in men with Locally Advanced Disease

Investigators have reported, at the American Society for Therapeutic Radiation and Oncology (ASTRO) 50th Annual Meeting, that when radiation is added to anti-androgen therapy (ADT), survival rates are increased by 50% in men receiving only ADT. "This randomized trial is the first to show that men with locally advanced prostate cancer will survive substantially longer [...]

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