Dynamics of Bone Mineral Density During Intermittent Androgen Deprivation for Men with Biochemical Recurrence of Prostate Cancer

It has been clearly shown that androgen deprivation therapy (ADT) for the treatment of prostate cancer leads to loss of bone mineral density (BMD) and increased fracture risk. More importantly, loss of BMD shortens survival time. (see my post of December 27, 2009 “On the Horizon – Dasatinib A Drug to Inhibit the growth of [...]

Timing IADT, Can “On Cycle” Time Periods Predict Outcomes?

A study by Yu et al., of men with a rising PSA after failed radical prostatectomy or radiation therapy who were placed on intermittent androgen deprivation therapy (IADT) indicated that the length of their first “off cycle” correlates with their expected time to developing castrate resistant prostate cancer (CRPC) and to their prostate cancer-specific mortality. [...]

FDA Clears a Six-Month Trelstar Formulation for the Palliative Treatment of Advanced Prostate Cancer

Watson Pharmaceuticals announced that it has received approval from the FDA for its new six-month intramuscular formulation, Trelstar, a (triptorelin pamoate for injectable suspension) 22.5 mg. Trelstar 22.5 mg is a gonadotropin releasing hormone (GnRH) agonist used for the palliative treatment of advanced prostate cancer. […]

Coffee, Coffee – I Need My Cup of Coffee!

Many of us once considered drinking coffee nothing but a bad habit, but now it looks as if drinking coffee is actually a good thing for us. Researchers are finding more and more benefits from drinking coffee, from preventing cancer to fighting fatigue. […]

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