Hormone Therapy - malecare.org

A New Phase III Trial of ODM-201 for Men with Castrate Resistant Prostate Cancer without Visible Metastases

Bayer HealthCare and Orion Corporation (a Finnish pharmaceutical company) have announced that they have begun enrollment in a randomized Phase III clinical trial of a new investigational treatment for men with advanced prostate cancer. ODM-201 is a novel, oral androgen receptor inhibitor. The trial named ARAMIS trial is a randomized, Phase III, multi-center, double-blind, placebo-controlled [...]

By Malecare|2021-02-17T11:03:15-05:00September 21st, 2014|Advanced Prostate Cancer, Androgan Receptor Inhibitor, Drugs & Treatments, General Information, Hormone Therapy, OMD-201, Uncategorized|1 Comment

Depression In Men Receiving Androgen Deprivation Therapy (ADT)

Yesterday I wrote about the cognitive effects of hormone therapy (ADT), today’s topic is about depression in men on ADT. It is commonly known that men on ADT often experience many physical and psychological side effects of the treatment. One of these side effects to ADT may be associated with increased risk for depression, but [...]

By Malecare|2020-02-04T11:40:42-05:00September 16th, 2014|ADT, Advanced Prostate Cancer, Drugs & Treatments, Hormone Therapy, How We Live, Quality of Life, Research, Uncategorized, Understanding APC|2 Comments

Chemo-Brain and ADT for Advanced Prostate Cancer – Does It Exist?

When I went on my first round of hormone therapy (ADT) I experienced severe cognitive side effects. I found it impossible to concentrate, read and remember anything. I lost the ability to navigate the New York City subways no less drive my car to a destination. Occasionally, when I was attempting to navigate the subway [...]

By Malecare|2017-10-19T10:48:02-04:00September 15th, 2014|ADT, Advanced Prostate Cancer, General Information, Hormone Therapy, Me, Quality of Life, Research, Uncategorized, Understanding APC|5 Comments

Efficacy of Long-Term Treatment of > 5-10 Years with the LHRH Drug Leuprorelin (Lupron)

Popular culture tells us that primary androgen deprivation therapy with leuprorelin acetate (Lupron) will not work for longer than two years! This is a significant and very problematic statement given that all of us with metastatic prostate cancer rely on delaying the move to any other treatments, especially given their cost to the quality of [...]

By Malecare|2014-06-30T16:49:05-04:00June 30th, 2014|ADT, Advanced Prostate Cancer, Clinical Trials, Clinical Trials, Drugs & Treatments, Germany, Hormone Therapy, Uncategorized, Understanding APC|2 Comments

Limiting Lower Urinary Tract Symptoms in Men with Prostate Cancer

Prostate cancer is commonly associated with lower urinary tract symptoms (LUTS). The use of GnRH agonists or antagonists (first line ADT) is widely used as the primary treatment for advanced prostate cancer (pc) and/or to reduce prostate volume (TPV). It is thought that the ADT contributes to the development of LUTS. Researchers pooled multiple other [...]

By Malecare|2020-02-04T10:11:41-05:00June 26th, 2014|ADT, Advanced Prostate Cancer, Clinical Trials, Clinical Trials, Drugs & Treatments, Firmagon (degarelix), Hormone Therapy, Uncategorized, Understanding APC, United Kingdom - England, Northern Ireland, Scotland & Wales|0 Comments