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Efficacy of a Modified Androgen Blockade in Prostate Cancer Patients with Biochemical Failure

How to best treat men with a prostate cancer PSA only recurrence (biochemical recurrence) still remains controversial. Hormone therapy (ADT) using a combination of a 5-alpha reductase inhibitor and an antiandrogen without conventional gonadal androgen suppression (where testosterone levels are not suppressed) may allow control of the prostate-specific antigen (PSA) with less morbidity. METHODS: In [...]

By Malecare|2017-10-19T10:51:37-04:00December 21st, 2011|adjuvant therapy, Advanced Prostate Cancer, Drugs & Treatments, General Information, Hormone Therapy, Research, Uncategorized, Understanding APC|1 Comment

Some Interesting Epidemiological Information About Prostate Cancer

Prostate cancer is more prevalent in higher latitudes. This has been correlated with Vitamin D metabolism and its effect on tissue differentiation. Autopsies have shown that incidental prostate cancer is noted in 30% of men in the 6th decade of life and increases significantly through the ninth decade. These data have been reproduced in populations [...]

By Malecare|2017-10-19T10:51:52-04:00December 15th, 2011|Advanced Prostate Cancer, General Information, Uncategorized|0 Comments

The Expression Of Prostatic Acid Phosphatase In Prostate Cancer Bone Metastases

One of the major causes of prostate cancer morbidity and mortality is bone metastases. Currently, when it comes to treating prostate cancer metastases we are very limited in effective therapies that actually prolong survival. Kirschenbaum A, etal (Departments of Urology and Medicine Division of Pulmonary Diseases Division of Endocrinology, Metabolism, and Bone Diseases, Mount Sinai [...]

By Malecare|2017-10-19T10:51:53-04:00December 13th, 2011|Advanced Prostate Cancer, Bone Metastases, General Information, Metastases, Research, Uncategorized, Understanding APC|1 Comment

Hormone Therapy (ADT) Does Not Increase The Risk Of Cardiac Threats in Prostate Cancer

Again, prostate cancer confusion continues to reign. A recent study reported at the ASTRO (American Society for Radiation Oncology) conference claims that the addition of androgen deprivation therapy (ADT) in men with clinically localized prostate cancer was not associated with increased cardiovascular mortality. According to Jason A. Efstathiou, MD, Ph.D.l, of the Massachusetts General Hospital [...]

By Malecare|2017-10-19T10:51:54-04:00December 6th, 2011|Advanced Prostate Cancer, Drugs & Treatments, General Information, Hormone Therapy, Research, Uncategorized|0 Comments

Hormonal Therapy (ADT) Is Associated With An Increase of Thrombotic Events

A recent article in the journal Cancer reported that there is an association for men being treated for prostate cancer with androgen deprivation therapy (ADT) and a risk of developing blood clots. The article, written by Edhaie et al. analyzed the Surveillance, Epidemiology and End Results (SEER) –Medicare database to identify 154,611 men over the [...]

By Malecare|2017-10-19T10:51:54-04:00December 3rd, 2011|Advanced Prostate Cancer, Drugs & Treatments, General Information, Hormone Therapy, Research, Uncategorized, Understanding APC|0 Comments