General Information

FDA Approves New Indications for Prolia® (Denosumab) for the Treatment of Bone Loss in Men with Prostate Cancer Undergoing ADT

Amgen announced that the U.S. Food and Drug Administration (FDA) has approved two new indications for Prolia® (denosumab) as a treatment to increase bone mass in men receiving androgen deprivation therapy (ADT) for non-metastatic prostate cancer. Men receiving ADT are at high risk for developing fractures, including vertebral fractures, which can cause paralysis. "Bone loss [...]

By |2011-09-19T10:59:59-04:00September 19th, 2011|Advanced Prostate Cancer, Bone Mineral Density, Drugs & Treatments, FDA, General Information, Hormone Therapy, Prolia (denosumab), Uncategorized, Understanding APC|3 Comments
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Genetics & Calcium Might Increase Risk for Prostate Cancer In the African-American Men

A study by at Wake Forest Baptist Medical Center in Winston-Salem N.C., Keck School of Medicine at the University of Southern California (USC) and the Cancer Prevention Institute of California suggests that a high intake of calcium causes prostate cancer among African-American men who are genetically good absorbers of the mineral. According to Gary G. [...]

By |2017-10-19T10:52:04-04:00September 16th, 2011|Advanced Prostate Cancer, Diet, Diet and Supplements, General Information, genetics, Genomics, Research, Uncategorized, Understanding APC|0 Comments
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The Impact of Hypertriglyceridemia On Prostate Cancer Development in Men Over 60 Years

An interesting, but it makes sense type of study, was discussed about the relationship between high levels of triglycerides (TG) and the development of prostate cancer, including more aggresive prostate cancer. It of course follows suite that prostate cancer diagnosed with higher gleason scores (more aggressive) leads to more advanced prostate cancer. This study which [...]

By |2011-09-09T12:16:26-04:00September 9th, 2011|Advanced Prostate Cancer, General Information, Uncategorized, Understanding APC|0 Comments
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Morbidity and Treatment Regret in Men with Advanced Prostate Cancer

The question of today’s post is do men with advanced prostate cancer develop treatment regrets concurrent to their development of morbidity issues ( i.e.- myocardial infarction, congestive heart failure, angina, diabetes, stroke, circulation problems, inflammatory bowel disease, or amputation)? To answer this question researchers evaluated 795 men from the Comprehensive, Observational, Multicenter, Prostate Adenocarcinoma Registry [...]

By |2011-09-08T14:02:36-04:00September 8th, 2011|Advanced Prostate Cancer, General Information, How We Live, Research, Uncategorized, Understanding APC|1 Comment
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Cabozantinib, Promising, Still Controversial For the Treatment of Bone Mets in Prostate Cancer

Cabozantinib (cabo), has many of us prostate cancer survivor, educators and researchers simply scratching their heads. In trials, Cabozantinib demonstrated what some people have characterized as mind boggling activity against bone metastases. In trials the drug led to partial or complete resolution of bone scans in a substantial portion of patients with cancer, including prostate, [...]

By |2017-10-19T10:52:06-04:00August 24th, 2011|Advanced Prostate Cancer, Alpharadin (radium-223), cabozantinib, Drugs & Treatments, General Information, Imaging, Metastases, Research, Uncategorized, Understanding APC|3 Comments
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Identifying A New Pathway Explaining Resistance to Prostate Cancer Treatment

We al are very familiar with the significant problem in the treatment of prostate cancer, even therapies that initially work stop working and our disease continues to progress. The inevitable onset of this resistance to treatment with antiandrogens (ADT) such as Lupron or Zoladex is not limited just to this class of drugs. We have [...]

By |2017-10-19T10:52:07-04:00August 18th, 2011|abiraterone acetate, Advanced Prostate Cancer, Chemo Therapy Failure, Drugs & Treatments, General Information, Hormone Therapy, Research, Uncategorized, Understanding APC|10 Comments
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Decreased Prostate Cancer-Specific Survival of Men with BRCA2 Mutations and for Men from Breast Cancer Families

It is fairly common practice for those diagnosed with breast cancer to have genetic testing. Genetic testing is almost unheard of when men are diagnosed with prostate cancer. Current research shows that genetic testing for men with prostate cancer could provide important information about both potential treatment efficacy and prognosis. A recent look at the [...]

By |2017-10-19T10:52:09-04:00August 17th, 2011|Advanced Prostate Cancer, Drugs & Treatments, General Information, genetics, Genomics, Research, Uncategorized, Understanding APC|0 Comments
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Prostate Cancer Survivors Should be Prescribed Exercise

According to a report released recently by the UK charity Macmillan Cancer Support exercise can benefit cancer survivors, including prostate cancer survivors. This report disproves the theory that those suffering with cancer or who have beaten the disease should simply rest. Rest no more, exercise should be prescribed to those at all stages of cancer [...]

By |2017-10-19T10:52:10-04:00August 10th, 2011|Advanced Prostate Cancer, Drugs & Treatments, General Information, How We Live, Research, Uncategorized, Understanding APC|0 Comments
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