The Differences in Ketoconazole & Abiraterone (Zytiga)

Zytiga  (abiraterone acetate) and Ketoconazole (keto) are both widely used in prostate cancer therapy to treat men with advanced prostate cancer.   They both have a common mechanism of action, they both work by inhibiting the enzyme CYP17 that is responsible for androgen biosynthesis (creation).  Inhibiting CYP17 lowers testosterone levels, which results in prostate cancer tumor regression. Because [...]

Changes in Clinical Trials – The Addition of Patient Reported Outcomes

Recently,  the U.S. Food and Drug Administration (FDA), has begun to support the reporting and use of patient-reported outcome measures (PROMs) of symptoms as secondary end points in clinical trials for oncology treatment.  These outcomes measures are likely to become increasingly important for oncology patients as they will hopefully become part of the  drug label. [...]

An Important Announcement – Open Enrollment Period for Medicare

All of the Americans who receive their insurance benefits from Medicare need to become aware that the Medicare Open Enrollment Period will begin this coming October 15. What is the Medicare open enrollment period?During this open enrollment period you can make new choices and pick plans that work best for you depending upon your doctors [...]

The Impact of Prostate Cancer on the Quality of Life – A Canadian Survey

Prostate cancer can impact the quality of life, having a major effect on patients' day-to-day life and overall well-being. According to a new Canadian survey of men who have or have had prostate cancer, prostate cancer’s physical manifestations can also lead to psychological and social concerns, both of which are more pronounced for those with [...]

IMO Declares A Cancer Care Crisis in the U.S.

The state of cancer care is in crisis and getting worse.  There is an ever growing demand for cancer care, a shrinking workforce, rising healthcare costs and an increasing complexity of treatment of cancer.  According to the Institute of Medicine (IMO) cancer care in America is in a deep crisis! In analysing the current state [...]

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