Drugs & Treatments

Efficacy of a Modified Androgen Blockade in Prostate Cancer Patients with Biochemical Failure

How to best treat men with a prostate cancer PSA only recurrence (biochemical recurrence) still remains controversial. Hormone therapy (ADT) using a combination of a 5-alpha reductase inhibitor and an antiandrogen without conventional gonadal androgen suppression (where testosterone levels are not suppressed) may allow control of the prostate-specific antigen (PSA) with less morbidity. METHODS: In [...]

By Malecare|2017-10-19T10:51:37-04:00December 21st, 2011|adjuvant therapy, Advanced Prostate Cancer, Drugs & Treatments, General Information, Hormone Therapy, Research, Uncategorized, Understanding APC|1 Comment

A Look at the Status of Cancer Vaccines – Emerging Treatments

From very early on, researchers and doctors have dreamed of using the body’s own immune system to fight cancer. The big question has been why doesn’t the immune system attack the tumor cells that invade healthy tissue? The really good news is that finally science is catching up with this vision. Therapeutic cancer vaccines that [...]

By Malecare|2011-12-20T14:34:32-05:00December 20th, 2011|Advanced Prostate Cancer, Clinical Trials, Clinical Trials, Drugs & Treatments, ipilimumab, Prostvac, Provenge, Research, Uncategorized, Understanding APC, vaccines, Yervoy|1 Comment

Dr. Mark Scholz Discusses Treatment Issues For Advanced Prostate Cancer

At the recent 2011 Prostate Cancer Research Institute Dr. Mark Scholz discussed care issues for men with advanced metastatic prostate cancer. In his presentation he stressed the importance of closely monitoring each man’s individual, on-going response to treatment to determine its effectiveness. He made a case that without close monitoring; treatment decisions would lag behind [...]

By Malecare|2017-10-19T10:51:52-04:00December 17th, 2011|Advanced Prostate Cancer, carboplatin, Chemo Therapy, Custirsen, Drugs & Treatments, Uncategorized, Understanding APC|1 Comment

Osteonecrosis Of The Jaw While Taking Zometa & Xgeva

The use of denosumab (Xgeva) as an alternative to the more commonly prescribed zoledronic acid (Zometa) to slow down the development of bone metastases in men with advanced prostate cancer is becoming more common. The most common concern for men taking Zometa and now Xgeva has been osteonecrosis of the jaw. Osteonecrosis of the jaw [...]

By Malecare|2017-10-19T10:51:53-04:00December 12th, 2011|Advanced Prostate Cancer, bisphosphonates, denosumab - Prolia, denosumab - Xgeva, Drugs & Treatments, Uncategorized, Understanding APC, Zometa|9 Comments

Hormone Therapy (ADT) Does Not Increase The Risk Of Cardiac Threats in Prostate Cancer

Again, prostate cancer confusion continues to reign. A recent study reported at the ASTRO (American Society for Radiation Oncology) conference claims that the addition of androgen deprivation therapy (ADT) in men with clinically localized prostate cancer was not associated with increased cardiovascular mortality. According to Jason A. Efstathiou, MD, Ph.D.l, of the Massachusetts General Hospital [...]

By Malecare|2017-10-19T10:51:54-04:00December 6th, 2011|Advanced Prostate Cancer, Drugs & Treatments, General Information, Hormone Therapy, Research, Uncategorized|0 Comments

Hormonal Therapy (ADT) Is Associated With An Increase of Thrombotic Events

A recent article in the journal Cancer reported that there is an association for men being treated for prostate cancer with androgen deprivation therapy (ADT) and a risk of developing blood clots. The article, written by Edhaie et al. analyzed the Surveillance, Epidemiology and End Results (SEER) –Medicare database to identify 154,611 men over the [...]

By Malecare|2017-10-19T10:51:54-04:00December 3rd, 2011|Advanced Prostate Cancer, Drugs & Treatments, General Information, Hormone Therapy, Research, Uncategorized, Understanding APC|0 Comments

Clinical Trial For Revlimid To Be Halted!

According to Bloomberg News Celgene Corp. said it will stop a study (Mainsail) of its blood-cancer pill Revlimid as a treatment for prostate cancer because the drug failed to help patients more than chemotherapy and steroids alone. This conclusion was drawn after the data-monitoring panel found the drug did not meet its primary goal of [...]

By Malecare|2011-12-01T13:28:33-05:00December 1st, 2011|Advanced Prostate Cancer, Clinical Trials, Clinical Trials, Drugs & Treatments, Uncategorized|0 Comments

XGEVA Delays The Onset Of Bone Metastases In Men With Non-Metastastic Castrate Resistant Prostate Cancer

Amgen announced that they have published the results from their Phase 3 trial (the '147 study) that evaluated XGEVA® (denosumab) for use in preventing or delaying the onset of bone metastases in men with non-metastatic castration-resistant prostate cancer (CRPC). The results were published in The Lancet. The study found XGEVA significantly prolonged bone metastasis-free survival, [...]

By Malecare|2020-02-04T10:43:48-05:00November 23rd, 2011|Advanced Prostate Cancer, bisphosphonates, Clinical Trials, Clinical Trials, denosumab - Xgeva, Drugs & Treatments, Metastases, Uncategorized, Understanding APC|2 Comments

Early Versus Delayed Use of Hormone Therapy- An Analysis For Men with Advanced Prostate Cancer

Initially, when first used by Huggins and Hodges hormone therapy (ADT) was recommended to be used early on in prostate cancer disease progression. Eventually, the Veterans Administration Cooperative Urology Research Group (VACURG) studies reversed this early recommendation. After this study ADT was usually deferred until symptomatic progression. It was believed that ADT caused an alteration [...]

By Malecare|2017-10-19T10:51:55-04:00November 18th, 2011|Advanced Prostate Cancer, Drugs & Treatments, General Information, Hormone Therapy, Research, Uncategorized, Understanding APC|0 Comments

Combined Androgen Deprivation Therapy and Radiation Therapy for Locally Advanced Prostate Cancer:Positive Results

A group of researchers just reported positive results of a phase 3 trial showing that the addition of radiation therapy (RT) improves overall survival in men with locally advanced prostate cancer (T3 & T4) to androgen deprivation therapy (ADT) alone. The researchers used a sample of 1,057 men with locally advanced (T3 or T4) prostate [...]

By Malecare|2011-11-06T12:51:38-05:00November 6th, 2011|Advanced Prostate Cancer, Clinical Trials, Clinical Trials, Drugs & Treatments, General Information, Hormone Therapy, Radiotherapy, Uncategorized, Understanding APC|0 Comments