It was reported in the October 17th issue of the Journal of the National Cancer Institute by lead author Dr. Henry K. Tsai, from the Harvard Radiation Oncology Program in Boston, that the use of androgen deprivation therapy (ADT) appears to increase the risk of death from cardiovascular disease among men who undergo radical prostatectomy [...]
There is a rarely discussed, but well know association between low androgen levels and anemia in men on ADT. The underlying cause of anemia in men on ADT is believed to be the low levels of testosterone and dihydrotestosterone in the body. Dr. Strum et al. examined the severity of anemia in patients on ADT. [...]
Men undergoing Hormone Therapy (ADT) can experience many symptoms. One of the most common of these symptoms are hot flashes. The typical description of a hot flash includes an intense feeling of warmth in the face, head and upper body. Often, the feeling of warmth is accompanied by facial flushing, nausea and severe sweating. The [...]
Long recognized as a significant health issue for post-menopausal women, Osteoporosis also poses a significant risk to men on a Hormone Blockade (ADT). Osteoporosis, the loss of bone density, poses an immediate and direct risk of fractures to men on ADT! A decline in the serum testosterone in men on ADT correlates with a decline [...]
There has been along standing controversy pertaining to the timing of ADT initiation (i.e. early verses late). However, in 2002 the Cochrane meta-analysis (Nair B, Wilt T, MacDonald R et al., "Early versus Deferred Androgen Suppression in the Treatment of Advanced Prostate Cancer", Cochrane Database Syst Rev (2002); (1): CD003506) clarified this issue. Initiating early [...]